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MIRAGE
Fibrinogen alpha chain
Summary
- UniProt ID
- P06399
- Gene Symbol
-
- Fga
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Adaptive immunity
- Alternative splicing
- Blood coagulation
- Calcium
- Coiled coil
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Hydroxylation
- Innate immunity
- Metal-binding
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| fibrinogen complex |
| extracellular space |
| cell cortex |
| synapse |
| external side of plasma membrane |
| cell surface |
| platelet alpha granule |
| blood microparticle |
| GO Term |
|---|
| acute-phase response |
| cell-matrix adhesion |
| platelet aggregation |
| blood coagulation, common pathway |
| adaptive immune response |
| blood coagulation |
| response to toxic substance |
| fibrinolysis |
| innate immune response |
| positive regulation of exocytosis |
| GO Term |
|---|
| signaling receptor binding |
| metal ion binding |
| structural molecule activity |
| protein-macromolecule adaptor activity |
Sequence
MLSLRVACLILSLASTVWTADTGTTSEFIEAGGDIRGPRIVERQPSQCKETDWPFCSDEDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANNFDNTFGQVSEDLRRRIQILKRKVIEKAQQIQVLQKDVRDQLIDMKRLEVDIDIKIRSCKGSCSRSVSREINLKDYEGQQKQLEQVIAKDLLPAKDRQYLPAIKMSPVPDLVPGSFKSQLQEGPPEWKALTEMRQMRMELERPGKDGASRGDLPGDSRGDSATRGPGSKIENPMTPGHGGSGYWRPGSSGSGSDGNWGSGTTGSDDTGTWGAGSSRPSSGSGNLKPSNPDWGEFSEFGGSSSPATRKEYHTGKLVTSKGDKELLIGNEKVTSTGTSTTRRSCSKTITKTVLGNDGHREVVKEVVTSDDGSDCGDGMDLGLTHSFSGRLDELSRMHPELGSFYDSRFGSLTSNFKEFGSKTSDSDIFTDIENPSSHVPEFSSSSKTSTVRKQVTKSYKMADEAASEAHQEGDTRTTKRGRARTMRDCDDVLQTHPSGAQNGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRGSVLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYQGTAGDALMEGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVLWVPFRGADYSLWAVRMKIRPLVGQ
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Common Pathway of Fibrin Clot Formation | Rattus norvegicus |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | Rattus norvegicus |
| Integrin cell surface interactions | Rattus norvegicus |
| Integrin signaling | Rattus norvegicus |
| MAP2K and MAPK activation | Rattus norvegicus |
| Platelet degranulation | Rattus norvegicus |
| Post-translational protein phosphorylation | Rattus norvegicus |
| Regulation of IGF Activity by IGFBP | Rattus norvegicus |
| Regulation of TLR by endogenous ligand | Rattus norvegicus |
| p130Cas linkage to MAPK signaling for integrins | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11247 | disseminated intravascular coagulation | |
| DOID:1588 | thrombocytopenia | |
| DOID:2316 | brain ischemia | |
| DOID:2841 | asthma |
