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Glucocorticoid receptor

Summary

UniProt ID

P06537

Gene Symbol

Grl
Grl1
Nr3c1

Gene ID

14815

Organism

Mus musculus (house mouse)

External Links

GlyGen: P06537
PubChem: P06537
The O-GlcNAc Database: P06537
O-GlcNAcAtlas: P06537
Re-Glyco: P06537

Annotation

Keyword

3D-structure
Acetylation
Alternative initiation
Alternative splicing
Chromatin regulator
Cytoskeleton
DNA-binding
Isopeptide bond
Methylation
Mitochondrion
Nucleus
Phosphoprotein
Receptor
Reference proteome
Steroid-binding
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

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GO Term
membrane
protein-containing complex
synapse
nucleoplasm
cytosol
centrosome
spindle
nuclear speck
nucleus
cytoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
regulation of gluconeogenesis
glucocorticoid metabolic process
regulation of glucocorticoid biosynthetic process
synaptic transmission, glutamatergic
regulation of DNA-templated transcription
positive regulation of neuron apoptotic process
positive regulation of transcription by RNA polymerase II
adrenal gland development
mammary gland duct morphogenesis
neuroinflammatory response

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GO Term
zinc ion binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
steroid binding
protein kinase binding
identical protein binding
sequence-specific DNA binding
DNA-binding transcription repressor activity, RNA polymerase II-specific
core promoter sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MDSKESLAPPGRDEVPSSLLGRGRGSVMDLYKTLRGGATVKVSASSPSVAAASQADSKQQRILLDFSKGSASNAQQQQQQQQQQQQQQQQQPQPDLSKAVSLSMGLYMGETETKVMGNDLGYPQQGQLGLSSGETDFRLLEESIANLNRSTSRPENPKSSTPAAGCATPTEKEFPQTHSDPSSEQQNRKSQPGTNGGSVKLYTTDQSTFDILQDLEFSAGSPGKETNESPWRSDLLIDENLLSPLAGEDDPFLLEGDVNEDCKPLILPDTKPKIQDTGDTILSSPSSVALPQVKTEKDDFIELCTPGVIKQEKLGPVYCQASFSGTNIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPVFNVIPPIPVGSENWNRCQGSGEDNLTSLGAMNFAGRSVFSNGYSSPGMRPDVSSPPSSSSTATGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATAGVSQDTSENANKTIVPAALPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSAWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASGNLLCFAPDLIINEQRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLLLSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSYCFQTFLDKSMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites