Tumor necrosis factor

Summary
UniProt ID
P06804
Gene Symbol
  • Tnf
  • Tnfa
  • Tnfsf2
Gene ID
21926
Organism
Mus musculus (house mouse)
PubChem
P06804
Re-Glyco
P06804
Sequence
MSTESMIRDVELAEEALPQKMGGFQNSRRCLCLSLFSFLLVAGATTLFCLLNFGVIGPQRDEKFPNGLPLISSMAQTLTLRSSSQNSSDKPVAHVVANHQVEEQLEWLSQRANALLANGMDLKDNQLVVPADGLYLVYSQVLFKGQGCPDYVLLTHTVSRFAISYQEKVNLLSAVKSPCPKDTPEGAELKPWYEPIYLGGVFQLEKGDQLSAEVNLPKYLDFAESGQVYFGVIAL
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
83 O-linked (GalNAc...) serine; in soluble form
86
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 6 entries
Pathway Name Organism
Regulation of TNFR1 signaling Mus musculus
TNF signaling Mus musculus
TNFR1-induced NF-kappa-B signaling pathway Mus musculus
TNFR1-induced proapoptotic signaling Mus musculus
TNFR1-mediated ceramide production Mus musculus
TNFR2 non-canonical NF-kB pathway Mus musculus
Disease
Displaying all 9 entries
DO ID Disease Name Source
DOID:0050156 idiopathic pulmonary fibrosis
DOID:0050589 inflammatory bowel disease
DOID:1123 spondyloarthropathy
DOID:12930 dilated cardiomyopathy
DOID:1712 aortic valve stenosis
DOID:2377 multiple sclerosis
DOID:4079 heart valve disease
DOID:6000 congestive heart failure
DOID:7148 rheumatoid arthritis

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025