Complement component C8 alpha chain

Summary
UniProt ID
P07357
Gene Symbol
  • C8A
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0011419
GlyConnect
GlyGen
P07357
PubChem
P07357
The O-GlcNAc Database
P07357
Annotation
Keyword
  • 3D-structure
  • Cell membrane
  • Cleavage on pair of basic residues
  • Complement alternate pathway
  • Direct protein sequencing
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Membrane attack complex
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Transmembrane beta strand
Gene Ontology (GO)
Site Annotations
Displaying 1 entry
Position Description
43 Not glycosylated
Sequence
MFAVVFFILSLMTCQPGVTAQEKVNQRVRRAATPAAVTCQLSNWSEWTDCFPCQDKKYRHRSLLQPNKFGGTICSGDIWDQASCSSSTTCVRQAQCGQDFQCKETGRCLKRHLVCNGDQDCLDGSDEDDCEDVRAIDEDCSQYEPIPGSQKAALGYNILTQEDAQSVYDASYYGGQCETVYNGEWRELRYDSTCERLYYGDDEKYFRKPYNFLKYHFEALADTGISSEFYDNANDLLSKVKKDKSDSFGVTIGIGPAGSPLLVGVGVSHSQDTSFLNELNKYNEKKFIFTRIFTKVQTAHFKMRKDDIMLDEGMLQSLMELPDQYNYGMYAKFINDYGTHYITSGSMGGIYEYILVIDKAKMESLGITSRDITTCFGGSLGIQYEDKINVGGGLSGDHCKKFGGGKTERARKAMAVEDIISRVRGGSSGWSGGLAQNRSTITYRSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEAKRQNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCRCQCRLGSLGAACEQTQTEGAKADGSWSCWSSWSVCRAGIQERRRECDNPAPQNGGASCPGRKVQTQAC
Glycosylation Sites
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Regulation of Complement cascade Homo sapiens
Terminal pathway of complement Homo sapiens

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024