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MIRAGE
Complement component C8 beta chain

Summary
UniProt ID
P07358
Gene Symbol
  • C8B
Gene ID
732
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011420
GlyConnect
GlyGen
P07358
PubChem
P07358
Re-Glyco
P07358
Annotation
Keyword
  • 3D-structure
  • Complement alternate pathway
  • Direct protein sequencing
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Membrane attack complex
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Target cell membrane
  • Transmembrane beta strand
Gene Ontology (GO)
Displaying all 7 entries
GO Term
extracellular vesicle
membrane attack complex
extracellular region
extracellular space
plasma membrane
membrane
extracellular exosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
protein-containing complex binding
Annotation information from UniProt.
Sequence
MKNSRTWAWRAPVELFLLCAALGCLSLPGSRGERPHSFGSNAVNKSFAKSRQMRSVDVTLMPIDCELSSWSSWTTCDPCQKKRYRYAYLLQPSQFHGEPCNFSDKEVEDCVTNRPCGSQVRCEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCRRIYKKCQHEMDQYWGIGSLASGINLFTNSFEGPVLDHRYYAGGCSPHYILNTRFRKPYNVESYTPQTQGKYEFILKEYESYSDFERNVTEKMASKSGFSFGFKIPGIFELGISSQSDRGKHYIRRTKRFSHTKSVFLHARSDLEVAHYKLKPRSLMLHYEFLQRVKRLPLEYSYGEYRDLFRDFGTHYITEAVLGGIYEYTLVMNKEAMERGDYTLNNVHACAKNDFKIGGAIEEVYVSLGVSVGKCRGILNEIKDRNKRDTMVEDLVVLVRGGASEHITTLAYQELPTADLMQEWGDAVQYNPAIIKVKVEPLYELVTATDFAYSSTVRQNMKQALEEFQKEVSSCHCAPCQGNGVPVLKGSRCDCICPVGSQGLACEVSYRKNTPIDGKWNCWSNWSSCSGRRKTRQRQCNNPPPQNGGSPCSGPASETLDCS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
70 C-linked (Man) tryptophan
73 C-linked (Man) tryptophan
101 N-linked (GlcNAc...) asparagine
243 N-linked (GlcNAc...) asparagine
551 C-linked (Man) tryptophan
554 C-linked (Man) tryptophan
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Regulation of Complement cascade Homo sapiens
Terminal pathway of complement Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0060302 type II complement component 8 deficiency
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025