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Pro-epidermal growth factor

Summary

UniProt ID

P07522

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

Annotation

Keyword

Direct protein sequencing
Disulfide bond
EGF-like domain
Glycoprotein
Growth factor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **31 - 40** of 43 in total

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GO Term
positive regulation of receptor internalization
epidermal growth factor receptor signaling pathway
positive regulation of peptidyl-threonine phosphorylation
positive regulation of MAPK cascade
regulation of receptor signaling pathway via JAK-STAT
ERBB2-EGFR signaling pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of ubiquitin-dependent protein catabolic process
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade

Displaying **all 3** entries
GO Term
extracellular space
plasma membrane
extracellular exosome

Displaying **all 8** entries
GO Term
calcium ion binding
transmembrane receptor protein tyrosine kinase activator activity
Wnt-protein binding
Wnt receptor activity
receptor ligand activity
guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
growth factor activity

Annotation information from UniProt.

Sequence

MLFSLTFLSVFLKITVLSVTAQQTRNCQSGPLERSGTTTYAAAGPPRFLIFLQGNSIFRINTDGTNHQQLVVDAGVSVVMDFHYKEERLYWVDLERQLLQRVFFNGSGQETVCKVDKNVSGLAINWIDGEILRTDRWKGVITVTDMNGNNSRVLLSSLKRPANILVDPTERLIFWSSVVTGNLHRADLGGMDVKTLLEAPERISVLILDILDKRLFWAQDGREGSHGYIHSCDYNGGSIHHIRHQARHDLLTMAIFGDKILYSALKEKAIWIADKHTGKNVVRVNLDPASVPPRELRVVHLHAQPGTENRAQASDSERCKQRRGQCLYSLSERDPNSDSSACAEGYTLSRDRKYCEDVNECALQNHGCTLGCENIPGSYYCTCPTGFVLLPDGKRCHELVACPGNRSECSHDCILTSDGPLCICPAGSVLGKDGKTCTGCSFSDNGGCSQICLPLSLASWECDCFPGYDLQLDRKSCAASMGPQPFLLFANSQDIRHMHFDGTDYKTLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANLDGSQRERRITEGVDTPEGLAVDWIGRRIYWTDSGKSVIEGSDLSGKHHQIIIKESISRPRGIAVHPKARRLFWTDTGMSPRIESSSLQGSDRTLIASSNLLEPSGIAIDYLTDTLYWCDTKLSVIEMADLDGSKRRRLTQNDVGHPFSLAVFEDHVWFSDWAIPSVIRVNKRTGQNRVRLRGSMLKPSSLVVVHPLAKPGADPCLHRNGGCEHICQESLGTAQCLCREGFVKAPDGKMCLTRKDDQILAGDNADLSKEVASLDNSPKAYVPDDDRTESSTLVAEIMVSGLNYEDDCGPGGCGSHAHCISEGEAAVCQCLKGFAGDGNLCSDIDECELGSSDCPPTSSRCINTEGGYVCQCSEGYEGDGIYCLDVDECQQGSHGCSENATCTNTEGGYNCTCAGCPSAPGLPCPDSTSPSLLGKDGCHWVRNSNTGCPPSYDGYCLNGGVCMYVESVDRYVCNCVIGYIGERCQHRDLRWWKLRHADYGQRHDITVVSVCVVALALLLLLGMWGTYYYRTRKQLSESSKKPSEESSSNVSSNGPDSSGAGVSSGPQPWFVVLEEHQQPKNGRLPAAGTNGAVVEAGLSSSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
105	N-linked (GlcNAc...) asparagine	UniProt
118	N-linked (GlcNAc...) asparagine	UniProt
149	N-linked (GlcNAc...) asparagine	UniProt
405	N-linked (GlcNAc...) asparagine	UniProt
930	N-linked (GlcNAc...) asparagine	UniProt
941	N-linked (GlcNAc...) asparagine	UniProt