GlyCosmos Portal

Submissions

Prosaposin

Summary

UniProt ID

P07602

Gene Symbol

PSAP
GLBA
SAP1

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011421

GlyConnect

1645

GlyGen

P07602

PubChem

P07602

The Human Metabolome Database

HMDBP01673

The O-GlcNAc Database

P07602

RaftProt

P07602

O-GlcNAcAtlas

P07602

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disease variant
Disulfide bond
Gangliosidosis
Gaucher disease
Glycoprotein
Lysosome
Metachromatic leukodystrophy
Neurodegeneration
Parkinson disease
Parkinsonism
Reference proteome
Repeat
Secreted
Signal
Sphingolipid metabolism

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
regulation of autophagy
regulation of lipid metabolic process
prostate gland growth
epithelial cell differentiation involved in prostate gland development
positive regulation of beta-galactosidase activity
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
ganglioside GM1 transport to membrane
sphingolipid metabolic process
lysosomal transport

Displaying entries **1 - 10** of 11 in total

1

2

Next ›

Last »
GO Term
intracellular membrane-bounded organelle
collagen-containing extracellular matrix
azurophil granule membrane
extracellular exosome
extracellular region
extracellular space
lysosome
lysosomal membrane
plasma membrane
late endosome

Displaying entry **11 - 11** of 11 in total

« First

‹ Prev

1

2
GO Term
phospholipid binding

Site Annotations

Displaying 1 entry
Position	Description
215	Not glycosylated; in variant MLDSAPB Ile-217

Annotation information from UniProt.

Sequence

MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 20** of 23 in total

« First

‹ Prev

1

2

3

Next ›

Last »
Position	Description	PubMed ID	GlyTouCan ID	Source
217			G74724QE	GlyGen GlyConnect
281			G57321FI	GlyGen
289			G57321FI	GlyGen
331				GlyGen
332	N-linked (GlcNAc...) asparagine	19159218 19167329	G87399DK G08609CW G53075ES G50856PC G82443XX G52890YB G05962QB G78649WQ G76417NN G15169WU G70232NH G69521XL G70888PK G06247RL G47518TP G35541EV G93718GY G13131HA G49755GI G20312EM G80075MS G11629QQ G57776ZS G68490OW G60834IK G86880BF G90382BL G63889NK G80479JV G85282JO G20528HD G94470IW G87123QX G79666IR G81263BG G92135MA G34989PA G81198YO G47012YE G45395BF G07246CJ G85554PZ G10819WX G14972EH G43223CG G37412TK G31986NC G08918WF G00912UN G58087IP G27915IV G89098OM G11911BT G87389XI G61256FT G45359RY G70441OD G87661QW G36442WJ G17208MA G76295SF G15664MX G80223IX G27126ED G04657PL G25451PN G27058EU G84452RH G85582CB G83460ZZ G23984SE G10773YW G96091TT G37509XX G51640FO G70223PD G41071NU G07755XJ G49018RC G72747WU G59626AS G08290VR G14994KB G92406TI G41840AI G01650EU G48584BU G70101JE G80920RR G01485JJ G42124LM G02886BB G65092SV G78059CC G90659AW G77547TA G64409MC G80333GO G59924QI G12313PD G20030CU G93500PH G62765YT G64527OM G62894KT G11870QZ G47644PP G72791KH G95177YH G36191CD G90734RJ G28541PG G72735IY G85269DF G72291OX G95865ZB G05724UK G31852PQ G90575OW G34527RW G59471TH G23719VF G33609NS G39446WN G11314AS G12398HZ G29880MM G39188ZX G41247ZX G80966KZ G25637MV G50282JC G98140IX G28663KH G57776ZU G36379GD G02815KT G06110VR G00406II G84349RE G29905OR G64481DJ G09724ZC G92050GC G74724QE G92275SC G14669DU G28681TP G58001LT G37995HC G84225JN G89045VA	GlycoProtDB UniProt GlyGen GlyConnect
334			G49108TO	GlyGen The O-GlcNAc Database
391			G57321FI	GlyGen
393			G57321FI	GlyGen
397			G57321FI	GlyGen
401			G57321FI	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
G alpha (i) signalling events	Homo sapiens
Glycosphingolipid catabolism	Homo sapiens
Neutrophil degranulation	Homo sapiens
Peptide ligand-binding receptors	Homo sapiens
Platelet degranulation	Homo sapiens

Human Protein Atlas

ENSG00000197746

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Displaying entries **31 - 40** of **265** in total

« First

‹ Prev

1

2

3

4

5

6

7

8

…

Next ›

Last »
DO ID	Disease Name	Source
DOID:0110473	autosomal recessive nonsyndromic deafness 18A	DisGeNET
DOID:0110474	autosomal recessive nonsyndromic deafness 18B	DisGeNET
DOID:0110475	autosomal recessive nonsyndromic deafness 1A	DisGeNET
DOID:0110476	autosomal recessive nonsyndromic deafness 1B	DisGeNET
DOID:0110477	autosomal recessive nonsyndromic deafness 2	DisGeNET
DOID:0110478	autosomal recessive nonsyndromic deafness 20	DisGeNET
DOID:0110479	autosomal recessive nonsyndromic deafness 21	DisGeNET
DOID:0110480	autosomal recessive nonsyndromic deafness 22	DisGeNET
DOID:0110481	autosomal recessive nonsyndromic deafness 23	DisGeNET
DOID:0110482	autosomal recessive nonsyndromic deafness 24	DisGeNET

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements