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T-cell surface glycoprotein CD3 epsilon chain
Summary
- UniProt ID
- P07766
- Gene Symbol
-
- CD3E
- T3E
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Cell membrane
- Disulfide bond
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi apparatus |
| plasma membrane |
| cell-cell junction |
| T cell receptor complex |
| alpha-beta T cell receptor complex |
| gamma-delta T cell receptor complex |
| cell body |
| immunological synapse |
| endoplasmic reticulum |
| external side of plasma membrane |
Sequence
MQSGTHWRVLGLCLLSVGVWGQDGNEEMGGITQTPYKVSISGTTVILTCPQYPGSEILWQHNDKNIGGDEDDKNIGSDEDHLSLKEFSELEQSGYYVCYPRGSKPEDANFYLYLRARVCENCMEMDVMSVATIVIVDICITGGLLLLVYYWSKNRKAKAKPVTRGAGAGGRQRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRRI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 55 |
|
|||
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream TCR signaling | Homo sapiens |
| Generation of second messenger molecules | Homo sapiens |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| PD-1 signaling | Homo sapiens |
| Phosphorylation of CD3 and TCR zeta chains | Homo sapiens |
| Translocation of ZAP-70 to Immunological synapse | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
