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Uromodulin

Summary

UniProt ID

P07911

Gene Symbol

UMOD

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011425

GlyConnect

GlyGen

P07911

PubChem

P07911

RaftProt

P07911

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Ciliopathy
Cilium
Direct protein sequencing
Disease variant
Disulfide bond
EGF-like domain
GPI-anchor
Innate immunity
Nephronophthisis
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

Displaying entries **31 - 40** of 46 in total

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GO Term
juxtaglomerular apparatus development
metanephric ascending thin limb development
metanephric distal convoluted tubule development
metanephric thick ascending limb development
protein localization to vacuole
neutrophil migration
chaperone-mediated protein folding
intracellular chloride ion homeostasis
cellular response to unfolded protein
ERAD pathway

Displaying entries **1 - 10** of 13 in total

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GO Term
membrane
ciliary membrane
extracellular exosome
basolateral plasma membrane
apical plasma membrane
spindle pole
endoplasmic reticulum
extrinsic component of membrane
Golgi lumen
cell surface

Displaying **all 2** entries
GO Term
IgG binding
calcium ion binding

Annotation information from UniProt.

Sequence

MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLNLGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 18** of 18 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
292			G22355FZ	GlyGen GlyConnect
296			G22625SJ G49874UX G60145BJ	GlyGen GlyConnect
322	N-linked (GlcNAc...) (complex) asparagine	22171320 32616672 33196145 35273390	G57835AK G94310CV G52848YE G90542MP G90787TS G73027HY G57581QG G74381CZ G78726CB G87399DK G53193KA G13191RB G48488CO G05813WO G16774YZ G53075ES G69834CE G94531EZ G79565XA G60227QI G27322BI G42459UQ G35697OJ G37773JL G94665LC G11115RO G56318NV G60439QY G66088HZ G94876HV G19469VZ G49305IN G67164EE G72886NH G71906BW G39595FH G81637OR G80319WU G92681HQ G71463BG G23811SR G26935KA G82894XV G50856PC G84735GS G56499YQ G82443XX G31532GK G95046LV G77023TY G54018RP G67173FM G39471UU G05962QB G64394MX G11611PG G78649WQ G12341GU G15169WU G33241WC G57955DP G70232NH G91413ZX G09118YK G41981MA G69521XL G29972TM G78030KJ G49084LP G03895SR G23345GE G34617SM G93718GY G76294TY G37881RL G40554DX G80075MS G38022PE G57776ZS G65449BO G69170UT G11671GQ G51098AA G75120WS G90382BL G91473PK G49739MP G90093AU G12222NC G34989PA G81198YO G52676LZ G99808VS G82811EP G17689DH G45395BF G96921ZU G47007PV G59536GA G65540UB G43223CG G64275UO G14047PA G77252PU G32659RY G57565TQ G61256FT G17540HT G46185ND G47975JA G76295SF G15664MX G11041DA G27058EU G53752TA G24413UY G83460ZZ G70223PD G29676WX G94047VH G72747WU G90987JA G45560HM G91365ZQ G08290VR G80920RR G01485JJ G62765YT G92974UU G47644PP G31852PQ G68668TB G41247ZX G80966KZ G54010QB G72197KC	GlycoProtDB UniProt GlyGen GlyConnect
396	N-linked (GlcNAc...) (complex) asparagine	22171320 32616672 32815518 33196145 35273390	G57835AK G90542MP G16774YZ G94531EZ G79565XA G60227QI G56318NV G60439QY G94876HV G19469VZ G49305IN G71906BW G80319WU G92681HQ G26935KA G82894XV G56499YQ G31532GK G54018RP G67173FM G33241WC G57955DP G91413ZX G09118YK G41981MA G78030KJ G03895SR G23345GE G76294TY G40554DX G38022PE G65449BO G69170UT G11671GQ G51098AA G75120WS G12222NC G52676LZ G99808VS G82811EP G17689DH G96921ZU G47007PV G14047PA G77252PU G32659RY G57565TQ G92551JA G61256FT G17540HT G46185ND G47975JA G11041DA G53752TA G24413UY G29676WX G94047VH G20425TQ G60033FS G90987JA G45560HM G59626AS G91365ZQ G92974UU G68668TB G80966KZ	UniProt GlyGen GlyConnect
504			G46524LG G47681UP	GlyGen GlyConnect
511			G46524LG G85228QD G49874UX	GlyGen GlyConnect
513	N-linked (GlcNAc...) (high mannose) asparagine; alternate	32616672 32815518 33196145	G57835AK G90542MP G13191RB G16774YZ G53075ES G94531EZ G79565XA G60227QI G56318NV G60439QY G94876HV G19469VZ G49305IN G67164EE G71906BW G39643OJ G18804KX G76915KR G39595FH G81637OR G80319WU G92681HQ G71463BG G26935KA G82894XV G50856PC G12793SR G99679NM G56499YQ G62461SM G82443XX G31532GK G61011OB G95046LV G32788FZ G63136LV G01160VV G60967DT G54018RP G67173FM G39471UU G05962QB G19603RR G11611PG G30740WO G90335NR G54740VA G78649WQ G67900CJ G18590ZR G46665ZP G12341GU G15169WU G33241WC G57955DP G70232NH G91413ZX G09118YK G50457PU G26101XB G55132BD G37818NZ G93656SY G41981MA G57888GL G69521XL G14547CB G99198RV G81124ET G70888PK G06247RL G78030KJ G03895SR G23345GE G35541EV G93718GY G44173IH G76294TY G85677PP G13131HA G37881RL G40554DX G49755GI G30799SW G46487SG G61806WR G75568BH G20312EM G80075MS G38022PE G57776ZS G16125XL G30751OD G56087PR G65449BO G69170UT G29545VG G41882MT G44753VC G39064KU G68490OW G52358QA G61053JL G46842SD G99668VU G31973KL G11671GQ G51098AA G77669RF G60834IK G86880BF G27947YN G52527GH G75120WS G28622IK G90382BL G25379SA G30970QQ G30248BL G29501UT G02315DX G85282JO G20528HD G37692EO G33416PL G81375TC G68833MP G81976CN G12222NC G94470IW G87123QX G96577RX G79666IR G81263BG G78701GW G92135MA G26403SG G98611JV G43734MM G75607BQ G34989PA G52676LZ G15488CF G99808VS G06330RB G40834TG G82811EP G43669FQ G17689DH G22310AV G45395BF G96921ZU G59324HL G07246CJ G04672QB G85554PZ G27516OE G47007PV G02628JF G20706XG G10819WX G40926MX G65540UB G14972EH G43223CG G64275UO G96416FQ G58954YZ G37412TK G54612UD G31615DN G31986NC G10846ZT G40574BA G82830MN G78787DI G08918WF G00912UN G14047PA G48414YA G77252PU G58087IP G32659RY G27915IV G89098OM G23505EP G99966GV G19116TW G57565TQ G61256FT G17540HT G46185ND G47975JA G70441OD G72797UR G70822IO G87661QW G66760KM G83646BJ G26759AS G17208MA G76295SF G15664MX G66621EA G03693IY G46691LC G25418HZ G27126ED G04657PL G11041DA G27058EU G53752TA G84452RH G46524LG G51653BI G24413UY G39619TI G83460ZZ G29676WX G94047VH G20425TQ G41071NU G75256KV G07755XJ G24835MQ G86182NS G35253PZ G85228QD G72747WU G90987JA G70619PT G45560HM G59626AS G91365ZQ G72398FA G84862VB G08290VR G92406TI G46503DX G70101JE G80920RR G73968GN G42124LM G02886BB G65092SV G23863VK G90659AW G14456RI G77547TA G45504EY G65000LJ G64409MC G59924QI G29299MO G37399XV G62765YT G92974UU G47950XN G11870QZ G47644PP G88891KO G10486CT G05049YU G31852PQ G68668TB G23719VF G39446WN G11314AS G41247ZX G80966KZ G02815KT G84349RE G92275SC G37995HC G72197KC G89045VA	UniProt GlyGen GlyConnect
			G57835AK G67596QA G16265OF G90542MP G16774YZ G69834CE G94531EZ G13238MZ G79565XA G60227QI G80961YY G56318NV G60439QY G66088HZ G03622KA G94876HV G19469VZ G49305IN G64160PL G62168IR G71906BW G23092XT G80319WU G92681HQ G26935KA G94788LD G82894XV G83487DQ G56499YQ G62461SM G31532GK G65766QU G02620FP G54018RP G67173FM G94222SG G15169WU G33241WC G57955DP G91413ZX G09118YK G72755ZH G41981MA G57888GL G47518TP G78030KJ G03895SR G23345GE G28209TJ G75325GX G76294TY G37881RL G40554DX G11629QQ G38022PE G50911BZ G65449BO G69170UT G11671GQ G51098AA G57097ZE G52527GH G75120WS G12222NC G69560OI G20014JD G52676LZ G40843RG G99808VS G09285QR G82811EP G17689DH G22310AV G96921ZU G47007PV G54330GJ G14047PA G48414YA G77252PU G28975ZZ G32659RY G57565TQ G99025FY G17540HT G46185ND G47975JA G98846QS G11041DA G53752TA G84452RH G24413UY G46422KL G29676WX G87932HN G82233NS G94047VH G49356OF G90987JA G06356OH G45560HM G91365ZQ G05724UK G68668TB G39188ZX G80966KZ G06110VR G45841FE	GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Asparagine N-linked glycosylation	Homo sapiens

Disease

Displaying entries **61 - 70** of **156** in total

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DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	DisGeNET
DOID:1073	renal hypertension	DisGeNET
DOID:1074	kidney failure	DisGeNET DisGeNET
DOID:1076	chronic pyelonephritis	DisGeNET
DOID:10763	hypertension	DisGeNET DisGeNET
DOID:10825	essential hypertension	DisGeNET DisGeNET
DOID:1678	chronic interstitial cystitis	DisGeNET
DOID:10952	nephritis	DisGeNET DisGeNET DisGeNET DisGeNET
DOID:11054	urinary bladder cancer	DisGeNET DisGeNET DisGeNET
DOID:1107	esophageal carcinoma	DisGeNET DisGeNET DisGeNET

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UniCarb-DR

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Acknowledgements