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Uromodulin

Summary

UniProt ID

P07911

Gene Symbol

UMOD

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011425

GlyConnect

GlyGen

P07911

PubChem

P07911

RaftProt

P07911

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Ciliopathy
Cilium
Direct protein sequencing
Disease variant
Disulfide bond
EGF-like domain
GPI-anchor
Innate immunity
Nephronophthisis
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

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GO Term
organ or tissue specific immune response
renal water homeostasis
glomerular filtration
lipid metabolic process
regulation of blood pressure
negative regulation of cell population proliferation
response to water deprivation
apoptotic signaling pathway
intracellular phosphate ion homeostasis
regulation of urine volume

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GO Term
endoplasmic reticulum
extrinsic component of membrane
Golgi lumen
cell surface
side of membrane
membrane
ciliary membrane
extracellular exosome
basolateral plasma membrane
apical plasma membrane

Displaying **all 2** entries
GO Term
IgG binding
calcium ion binding

Annotation information from UniProt.

Sequence

MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLNLGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine	32616672		UniProt GlyGen
76	N-linked (GlcNAc...) asparagine	32616672 35273390	G57835AK G90542MP G16774YZ G94531EZ G79565XA G60227QI G56318NV G60439QY G94876HV G19469VZ G49305IN G71906BW G80319WU G92681HQ G26935KA G82894XV G56499YQ G31532GK G54018RP G67173FM G33241WC G57955DP G91413ZX G09118YK G41981MA G78030KJ G03895SR G23345GE G76294TY G40554DX G38022PE G65449BO G69170UT G11671GQ G51098AA G75120WS G12222NC G52676LZ G99808VS G82811EP G17689DH G96921ZU G47007PV G14047PA G77252PU G32659RY G57565TQ G17540HT G46185ND G47975JA G11041DA G53752TA G24413UY G29676WX G94047VH G90987JA G45560HM G91365ZQ G92974UU G68668TB G80966KZ	UniProt GlyGen
80	N-linked (GlcNAc...) asparagine	32616672 35273390	G57835AK G90542MP G16774YZ G94531EZ G79565XA G60227QI G56318NV G60439QY G94876HV G19469VZ G49305IN G71906BW G80319WU G92681HQ G26935KA G82894XV G56499YQ G31532GK G54018RP G67173FM G33241WC G57955DP G91413ZX G09118YK G41981MA G78030KJ G03895SR G23345GE G76294TY G40554DX G38022PE G65449BO G69170UT G11671GQ G51098AA G75120WS G12222NC G52676LZ G99808VS G82811EP G17689DH G96921ZU G47007PV G14047PA G77252PU G32659RY G57565TQ G17540HT G46185ND G47975JA G11041DA G53752TA G24413UY G29676WX G94047VH G90987JA G45560HM G91365ZQ G92974UU G68668TB G80966KZ	UniProt GlyGen
89			G71142DF	GlyGen
154			G60554YG	GlyGen GlyConnect
225			G74722FL	GlyGen GlyConnect
232	N-linked (GlcNAc...) (complex) asparagine	22171320 26811476 32616672 35273390	G57835AK G90542MP G16774YZ G69834CE G94531EZ G79565XA G60227QI G31309XD G56318NV G60439QY G66088HZ G94876HV G19469VZ G49305IN G71906BW G39595FH G80319WU G92681HQ G68873DS G26935KA G82894XV G65414LI G50427EO G50856PC G12793SR G56499YQ G31532GK G63136LV G54018RP G67173FM G19603RR G46665ZP G15169WU G33241WC G57955DP G91413ZX G09118YK G93656SY G41981MA G69521XL G81124ET G70888PK G47518TP G78030KJ G49589RB G12261QD G03895SR G23345GE G76294TY G40554DX G11629QQ G38022PE G65449BO G69170UT G41882MT G75418YA G11671GQ G51098AA G77669RF G52527GH G75120WS G91473PK G40206WX G20528HD G63980BQ G12222NC G04854VP G94470IW G87123QX G79666IR G92135MA G26403SG G98611JV G75607BQ G81198YO G52676LZ G99808VS G82811EP G43669FQ G47012YE G17689DH G22310AV G45395BF G96921ZU G47007PV G20706XG G40926MX G59536GA G14972EH G43223CG G49642SA G95977AE G37412TK G10846ZT G40574BA G78787DI G00273SJ G08918WF G75983OB G00912UN G14047PA G48414YA G77252PU G32659RY G57565TQ G92551JA G61256FT G17540HT G46185ND G47975JA G96430BV G36442WJ G76295SF G15664MX G11041DA G53752TA G44305KR G24413UY G29676WX G94047VH G49018RC G46902YN G72747WU G90987JA G06356OH G45560HM G91365ZQ G46503DX G48584BU G80920RR G62765YT G92974UU G72735IY G68668TB G80966KZ G84349RE G28681TP G31685JQ G54010QB G89045VA G98129XB	UniProt GlyGen GlyConnect
252			G60145BJ	GlyGen GlyConnect
275	N-linked (GlcNAc...) (high mannose) asparagine	32616672 35273390	G57835AK G90542MP G16774YZ G94531EZ G79565XA G60227QI G35697OJ G56318NV G60439QY G94876HV G00433UK G19469VZ G49305IN G71906BW G80319WU G92681HQ G26935KA G82894XV G56499YQ G31532GK G54018RP G67173FM G33241WC G57955DP G91413ZX G09118YK G41981MA G78030KJ G03895SR G23345GE G76294TY G40554DX G38022PE G65449BO G69170UT G11671GQ G51098AA G75120WS G12222NC G76329HL G52676LZ G99808VS G82811EP G17689DH G96921ZU G47007PV G93683YO G00912UN G14047PA G77252PU G32659RY G57565TQ G17540HT G46185ND G47975JA G11041DA G53752TA G24413UY G29676WX G94047VH G90987JA G45560HM G91365ZQ G65092SV G23863VK G14456RI G74430RZ G64527OM G92974UU G23432EQ G50045TK G46687AB G72735IY G05724UK G68668TB G49874UX G39188ZX G80966KZ G06110VR G55220VL G60145BJ G66538GV G22355FZ	UniProt GlyGen GlyConnect
277			G49874UX	GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Asparagine N-linked glycosylation	Homo sapiens

Disease

Displaying entries **41 - 50** of **156** in total

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DO ID	Disease Name	Source
DOID:0110747	type 1 diabetes mellitus 8	DisGeNET
DOID:0110748	obsolete type 1 diabetes mellitus 9	DisGeNET
DOID:0110749	type 1 diabetes mellitus 10	DisGeNET
DOID:0110750	type 1 diabetes mellitus 11	DisGeNET
DOID:0110751	type 1 diabetes mellitus 12	DisGeNET
DOID:0110752	type 1 diabetes mellitus 13	DisGeNET
DOID:0110753	type 1 diabetes mellitus 15	DisGeNET
DOID:0110754	type 1 diabetes mellitus 17	DisGeNET
DOID:0110755	type 1 diabetes mellitus 18	DisGeNET
DOID:0110756	type 1 diabetes mellitus 19	DisGeNET

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Acknowledgements