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Beta-glucuronidase

Summary

UniProt ID

P08236

Gene Symbol

GUSB

Organism

Homo sapiens (human)

External Links

GlyConnect

1037

GlyGen

P08236

PubChem

P08236

The Human Metabolome Database

HMDBP00839

The O-GlcNAc Database

P08236

O-GlcNAcAtlas

P08236

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disease variant
Glycoprotein
Glycosidase
Lysosome
Mucopolysaccharidosis
Reference proteome
Signal

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
carbohydrate metabolic process
glucuronoside catabolic process
chondroitin sulfate catabolic process
hyaluronan catabolic process
glycosaminoglycan catabolic process
heparan sulfate proteoglycan catabolic process

Displaying **all 8** entries
GO Term
extracellular region
extracellular space
membrane
intracellular membrane-bounded organelle
azurophil granule lumen
ficolin-1-rich granule lumen
lysosomal lumen
extracellular exosome

Displaying **all 4** entries
GO Term
signaling receptor binding
carbohydrate binding
protein domain specific binding
beta-glucuronidase activity

Annotation information from UniProt.

Sequence

MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTTLPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGYYLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEYGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQSPTRVLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSLFT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
173	N-linked (GlcNAc...) asparagine	19159218	G60834IK G96430BV G15664MX G46524LG G39619TI G83460ZZ G72747WU G47448YK G08290VR G46503DX G25079LO G48584BU G70101JE G80920RR G06231AO G92062TF G45504EY G65000LJ G83633GK G62765YT G64527OM G31852PQ G41247ZX	UniProt GlyGen GlyConnect
174				GlyGen
272	N-linked (GlcNAc...) asparagine	12754519 16335952 19159218	G70441OD G46524LG G51653BI G83460ZZ G70101JE G80920RR G62765YT G64527OM G31852PQ G90575OW G41247ZX G50282JC G02815KT G84349RE G92050GC G74724QE G92275SC G28681TP	UniProt GlyGen GlyConnect
274			G49108TO	GlyGen The O-GlcNAc Database
420			G80920RR	UniProt GlyGen
631	N-linked (GlcNAc...) asparagine	19159218	G83460ZZ G70101JE G80920RR G62765YT G64527OM G31852PQ G39188ZX G41247ZX G02815KT G06110VR	UniProt GlyGen GlyConnect