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Macrophage colony-stimulating factor 1 receptor

Summary

UniProt ID

P09581

Gene Symbol

Csf1r
Csfmr
Fms

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003324
GlyGen: P09581
PubChem: P09581
RaftProt: P09581

Annotation

Keyword

3D-structure
ATP-binding
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Inflammatory response
Innate immunity
Phosphoprotein
Proto-oncogene
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 51 in total

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GO Term
axon guidance
positive regulation of cell population proliferation
negative regulation of cell population proliferation
positive regulation of gene expression
osteoclast differentiation
positive regulation of cell migration
positive regulation of bone mineralization
negative regulation of epithelial cell differentiation
positive regulation of chemokine production
regulation of mononuclear cell proliferation

Displaying **all 8** entries
GO Term
nucleoplasm
cell surface
plasma membrane
membrane
receptor complex
cell body
perikaryon
CSF1-CSF1R complex

Displaying **all 9** entries
GO Term
transmembrane receptor protein tyrosine kinase activity
ATP binding
growth factor binding
protein phosphatase binding
cytokine binding
protein homodimerization activity
protein tyrosine kinase activity
macrophage colony-stimulating factor receptor activity
organic cyclic compound binding

Annotation information from UniProt.

Sequence

MELGPPLVLLLATVWHGQGAPVIEPSGPELVVEPGETVTLRCVSNGSVEWDGPISPYWTLDPESPGSTLTTRNATFKNTGTYRCTELEDPMAGSTTIHLYVKDPAHSWNLLAQEVTVVEGQEAVLPCLITDPALKDSVSLMREGGRQVLRKTVYFFSPWRGFIIRKAKVLDSNTYVCKTMVNGRESTSTGIWLKVNRVHPEPPQIKLEPSKLVRIRGEAAQIVCSATNAEVGFNVILKRGDTKLEIPLNSDFQDNYYKKVRALSLNAVDFQDAGIYSCVASNDVGTRTATMNFQVVESAYLNLTSEQSLLQEVSVGDSLILTVHADAYPSIQHYNWTYLGPFFEDQRKLEFITQRAIYRYTFKLFLNRVKASEAGQYFLMAQNKAGWNNLTFELTLRYPPEVSVTWMPVNGSDVLFCDVSGYPQPSVTWMECRGHTDRCDEAQALQVWNDTHPEVLSQKPFDKVIIQSQLPIGTLKHNMTYFCKTHNSVGNSSQYFRAVSLGQSKQLPDESLFTPVVVACMSVMSLLVLLLLLLLYKYKQKPKYQVRWKIIERYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDSEGDSSYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSSDSFFKQDLDKEASRPLELWDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQEQARLERRDQDYANLPSSGGSSGSDSGGGSSGGSSSEPEEESSSEHLACCEPGDIAQPLLQPNNYQFC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
45	N-linked (GlcNAc...) asparagine	19017797		GlycoProtDB UniProt GlyGen
73	N-linked (GlcNAc...) asparagine	19017797		GlycoProtDB UniProt GlyGen
302	N-linked (GlcNAc...) asparagine			UniProt GlyGen
335	N-linked (GlcNAc...) asparagine			UniProt GlyGen
389	N-linked (GlcNAc...) asparagine		G07755XJ	GlycoProtDB UniProt GlyGen
410	N-linked (GlcNAc...) asparagine			UniProt GlyGen
449	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
478	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
491	N-linked (GlcNAc...) asparagine	16944957	G02886BB	GlycoProtDB UniProt GlyGen
803			G80920RR	GlyGen