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Lactase/phlorizin hydrolase

Summary

UniProt ID

P09849

Gene Symbol

LCT
LPH

Organism

Oryctolagus cuniculus (rabbit)

External Links

PubChem: P09849

Annotation

Keyword

Cell membrane
Direct protein sequencing
Glycoprotein
Glycosidase
Multifunctional enzyme
Reference proteome
Signal
Transmembrane helix
Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
glycosylceramide catabolic process
quercetin catabolic process
cellobiose catabolic process
lactose catabolic process

Displaying 1 entry
GO Term
external side of apical plasma membrane

Displaying **all 8** entries
GO Term
lactase activity
glycosylceramidase activity
phlorizin hydrolase activity
galactosylceramidase activity
glucosylceramidase activity
beta-glucosidase activity
protein homodimerization activity
cellobiose glucosidase activity

Annotation information from UniProt.

Sequence

MELFWSIVFTVLLSFSCRGSDWESDSNFISAAGPLTTDLLLSLQYPQGNQTSDFAAGGKDLYVCSQPLPAFLPEYFSSLRASEITHYKVFLSWAQLLPAGHSGDPDGNAVRCYRQLLEALRAAQLQPMVVLHHQHLPASSALRSAVFADLFAEYATFAFHAFGDLVGVWLTFSDLEAAIRELPQPESRASRLQLLTEAHRKAYEIYHQKYAAQGGKVSVVLQAEEISELLLESSTSALAKDSIDFLSLDLSYECQSEMSLPEKLSKLQTIEPKVKVFIFTLRLQDCPSSRKSPASLLFSFIEAINKDQVLTLGFDVNAFLNCSSTSKKSISCFLTDSLALQTDHERAARNSAPVSTYQRVWEMFAHQPRAERDAFLQDTFPQGFLWGVSTGAFNVEGGWAEGGRGPSVWDQFGHLKAAQGQATPEVASDSYYKWASDVALLRGLRAQVYKFSISWSRIFPMGRGSSPSPQGVAYYNKLIDSLLDSHIEPMATLFHWDLPQALQDEGGWQNESVVDAFVDYAAFCFSAFGNRVKLWVTFHEPWVMSYAGYGTGQHAPGISDPGIASFQVAHLVLKAHARTWHHYNSHHRPQQQGRVGIVLNSDWAEPLSPERPEDLAASERFLHFMLGWFAHPIFVDGDYPATMKAQIQQRNEQCPSPVAQLPEFTDTEKQLLKGSADFLGLSHYTSRLISKAPEDSCIPSYDTIGGFSQHTDPAWPQTSSPWIRVVPWGIRRLLQFVSLEYTKGKVPIYLAGNGMPIGESENLLSDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLMDGFEGPAGYSQRFGLYHVNFNESSKPRTPRKSAFLLTSIIEKNGFLTKAVKQPLPPNSAHLPSKTRASALPSEVPSKAKVVWEKFSNQTKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGNGVTDNSTGDIACDSYNQLDADLNVLRALKVKAYRFSLSWSRIFPTGTNSSINSHGVDYYNRLIDGLLASDIFPMVTLFHWDLPQALQDIGGWENPSLIDLFDSYADYCFQTFGDRVKFWITFNEPTYYSWWSYGSGTFPPNVNDPGWAPYRISHALIKAHARVYHTYDEKYRQSQNGVISLSLVAQWAEPKSPDVLRDVEAADRKMQFTLGWYAHPIFKTGDYPDAMKWKVGNRSELQHLATSRLPSFTEEEKSYIRGTADVFCLNTYSSKIVQHKTPALNPPSYEDDQELAEEEDTSWPTTAMNRAASFGMRRLLNWIKEEYGDIPIYITENGVGLTNPRLEDIDRIFYYKTYINEALKAYRLDGVNLRGYFAWSLMDNFEWLQGYTIKFGLYHVDFENVNRPRTARISASYYTELITNNGMPLPSEDEFVYGQFPEGFVWSTSTAAFQIEGAWRADGKGLGIWDTFTHTRLKIENDDIADVACDSYHKISEDVVALQNLAVTHYRFSISWSRILPDGTTNYINEAGLNYYVRLIDALLAANIKPQVTMYHFDLPQALQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVVAYHGYGTGLYAPGIYFRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAAKRYVQFMGGWFAHPIFKNGDYNEVMKTQIRERSLAAGLNESRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNFNYPSIMSTVDADRGVASIVDRSWPGSGSYWLKMTPFGFRRILNWIKEEYNNPPIYVTENGVSHRGDSYLNDTTRIYYLRSYINEALKAVQQDKVDLRGYTVWTLMDNFEWYTGFSDKFGLHFVNYSDPSLPRIPRESAKFYASIVRCNGFPDPAEGPHPCLLQPEDTDPTMSPVSQEEVQFLGLSLGSTEAETALYVLFSLMLLGVCGLAFLSYALCKSSKQRKKLSQQELSPVSSF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 15 in total

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Position	Description	Source
49	N-linked (GlcNAc...) asparagine	UniProt
321	N-linked (GlcNAc...) asparagine	UniProt
510	N-linked (GlcNAc...) asparagine	UniProt
821	N-linked (GlcNAc...) asparagine	UniProt
887	N-linked (GlcNAc...) asparagine	UniProt
932	N-linked (GlcNAc...) asparagine	UniProt
944	N-linked (GlcNAc...) asparagine	UniProt
987	N-linked (GlcNAc...) asparagine	UniProt
1033	N-linked (GlcNAc...) asparagine	UniProt
1172	N-linked (GlcNAc...) asparagine	UniProt