Lactase/phlorizin hydrolase

Summary
UniProt ID
P09849
Gene Symbol
  • LCT
  • LPH
Organism
Oryctolagus cuniculus (rabbit)
External Links
PubChem
P09849
Annotation
Keyword
  • Cell membrane
  • Direct protein sequencing
  • Glycoprotein
  • Glycosidase
  • Multifunctional enzyme
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Zymogen
Gene Ontology (GO)
Sequence
MELFWSIVFTVLLSFSCRGSDWESDSNFISAAGPLTTDLLLSLQYPQGNQTSDFAAGGKDLYVCSQPLPAFLPEYFSSLRASEITHYKVFLSWAQLLPAGHSGDPDGNAVRCYRQLLEALRAAQLQPMVVLHHQHLPASSALRSAVFADLFAEYATFAFHAFGDLVGVWLTFSDLEAAIRELPQPESRASRLQLLTEAHRKAYEIYHQKYAAQGGKVSVVLQAEEISELLLESSTSALAKDSIDFLSLDLSYECQSEMSLPEKLSKLQTIEPKVKVFIFTLRLQDCPSSRKSPASLLFSFIEAINKDQVLTLGFDVNAFLNCSSTSKKSISCFLTDSLALQTDHERAARNSAPVSTYQRVWEMFAHQPRAERDAFLQDTFPQGFLWGVSTGAFNVEGGWAEGGRGPSVWDQFGHLKAAQGQATPEVASDSYYKWASDVALLRGLRAQVYKFSISWSRIFPMGRGSSPSPQGVAYYNKLIDSLLDSHIEPMATLFHWDLPQALQDEGGWQNESVVDAFVDYAAFCFSAFGNRVKLWVTFHEPWVMSYAGYGTGQHAPGISDPGIASFQVAHLVLKAHARTWHHYNSHHRPQQQGRVGIVLNSDWAEPLSPERPEDLAASERFLHFMLGWFAHPIFVDGDYPATMKAQIQQRNEQCPSPVAQLPEFTDTEKQLLKGSADFLGLSHYTSRLISKAPEDSCIPSYDTIGGFSQHTDPAWPQTSSPWIRVVPWGIRRLLQFVSLEYTKGKVPIYLAGNGMPIGESENLLSDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLMDGFEGPAGYSQRFGLYHVNFNESSKPRTPRKSAFLLTSIIEKNGFLTKAVKQPLPPNSAHLPSKTRASALPSEVPSKAKVVWEKFSNQTKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGNGVTDNSTGDIACDSYNQLDADLNVLRALKVKAYRFSLSWSRIFPTGTNSSINSHGVDYYNRLIDGLLASDIFPMVTLFHWDLPQALQDIGGWENPSLIDLFDSYADYCFQTFGDRVKFWITFNEPTYYSWWSYGSGTFPPNVNDPGWAPYRISHALIKAHARVYHTYDEKYRQSQNGVISLSLVAQWAEPKSPDVLRDVEAADRKMQFTLGWYAHPIFKTGDYPDAMKWKVGNRSELQHLATSRLPSFTEEEKSYIRGTADVFCLNTYSSKIVQHKTPALNPPSYEDDQELAEEEDTSWPTTAMNRAASFGMRRLLNWIKEEYGDIPIYITENGVGLTNPRLEDIDRIFYYKTYINEALKAYRLDGVNLRGYFAWSLMDNFEWLQGYTIKFGLYHVDFENVNRPRTARISASYYTELITNNGMPLPSEDEFVYGQFPEGFVWSTSTAAFQIEGAWRADGKGLGIWDTFTHTRLKIENDDIADVACDSYHKISEDVVALQNLAVTHYRFSISWSRILPDGTTNYINEAGLNYYVRLIDALLAANIKPQVTMYHFDLPQALQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVVAYHGYGTGLYAPGIYFRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAAKRYVQFMGGWFAHPIFKNGDYNEVMKTQIRERSLAAGLNESRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNFNYPSIMSTVDADRGVASIVDRSWPGSGSYWLKMTPFGFRRILNWIKEEYNNPPIYVTENGVSHRGDSYLNDTTRIYYLRSYINEALKAVQQDKVDLRGYTVWTLMDNFEWYTGFSDKFGLHFVNYSDPSLPRIPRESAKFYASIVRCNGFPDPAEGPHPCLLQPEDTDPTMSPVSQEEVQFLGLSLGSTEAETALYVLFSLMLLGVCGLAFLSYALCKSSKQRKKLSQQELSPVSSF
Glycosylation Sites
Displaying entries 1 - 10 of 15 in total
Position Description PubMed ID GlyTouCan ID Source
49 N-linked (GlcNAc...) asparagine
321 N-linked (GlcNAc...) asparagine
510 N-linked (GlcNAc...) asparagine
821 N-linked (GlcNAc...) asparagine
887 N-linked (GlcNAc...) asparagine
932 N-linked (GlcNAc...) asparagine
944 N-linked (GlcNAc...) asparagine
987 N-linked (GlcNAc...) asparagine
1033 N-linked (GlcNAc...) asparagine
1172 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024