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Platelet glycoprotein VI

Summary

UniProt ID: P0C191
Gene Symbol: Gp6
Gene ID: 243816
Organism: Mus musculus (house mouse)

External Links

PubChem: P0C191
The Human Metabolome Database: HMDBP13515
Re-Glyco: P0C191

Annotation

Keyword: Blood coagulation Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
immune response-regulating signaling pathway
collagen-activated tyrosine kinase receptor signaling pathway	IDA	PMID
collagen-activated tyrosine kinase receptor signaling pathway	IMP	PMID
collagen-activated tyrosine kinase receptor signaling pathway	IBA	GO_REF
collagen-activated signaling pathway	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

signal transduction [inference]

immune response-regulating signaling pathway

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

collagen-activated tyrosine kinase receptor signaling pathway

collagen-activated signaling pathway

collagen-activated tyrosine kinase receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway

regulation of response to stimulus [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

collagen-activated tyrosine kinase receptor signaling pathway

collagen-activated signaling pathway

collagen-activated tyrosine kinase receptor signaling pathway

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISO	GO_REF
plasma membrane	IDA	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF
cell surface	IDA	PMID PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

membrane microdomain [inference]

membrane raft

tetraspanin-enriched microdomain

Displaying **all 4** entries
GO Term	Evidence Code	Reference
collagen binding	IDA	PMID PMID
collagen receptor activity	IMP	PMID
protein tyrosine kinase binding	ISO	GO_REF
protein tyrosine kinase binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding

protein-containing complex binding [inference]

collagen binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

collagen receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSPASPTFFCIGLCVLQVIQTQSGPLPKPSLQAQPSSLVPLGQSVILRCQGPPDVDLYRLEKLKPEKYEDQDFLFIPTMERSNAGRYRCSYQNGSHWSLPSDQLELIATGVYAKPSLSAHPSSAVPQGRDVTLKCQSPYSFDEFVLYKEGDTGSYKRPEKWYRANFPIITVTAAHSGTYRCYSFSSSSPYLWSAPSDPLVLVVTGLSATPSQVPTEESFPVTESSRRPSILPTNKISTTEKPMNITASPEGLSPPFGFAHQHYAKGNLVRICLGATIIIILLGLLAEDWHSRKKCLQHRMRALQRPLPPLPLA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
93	N-linked (GlcNAc...) asparagine			UniProt
244	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
GPVI-mediated activation cascade	Mus musculus
Platelet Adhesion to exposed collagen	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements