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Heat shock 70 kDa protein 1A

Summary

UniProt ID

P0DMW0

Gene Symbol

Hspa1a
Hsp70-1
Hspa1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P0DMW0
The O-GlcNAc Database: P0DMW0

Annotation

Keyword

ATP-binding
Acetylation
Chaperone
Cytoskeleton
Methylation
Nucleus
Phosphoprotein
Reference proteome
Secreted
Stress response

Gene Ontology (GO)

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GO Term
positive regulation of T cell mediated cytotoxicity
defense response
lysosomal transport
negative regulation of cell population proliferation
positive regulation of gene expression
negative regulation of cell growth
positive regulation of interleukin-8 production
positive regulation of microtubule nucleation
protein stabilization
chaperone cofactor-dependent protein refolding

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GO Term
perinuclear region of cytoplasm
ribonucleoprotein complex
inclusion body
aggresome
basolateral plasma membrane
apical plasma membrane
nuclear speck
mitochondrion
cytosol
membrane raft

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GO Term
G protein-coupled receptor binding
protease binding
signaling receptor binding
enzyme binding
NF-kappaB binding
misfolded protein binding
C3HC4-type RING finger domain binding
heat shock protein binding
denatured protein binding
ubiquitin protein ligase binding

Annotation information from UniProt.

Sequence

MAKKTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVVNDGDKPKVQVNYKGENRSFYPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRERVAAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDSNTLAEKEEFVHKREELERVCNPIISGLYQGAGAPGAGGFGAQAPKGGSGSGPTIEEVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
AUF1 (hnRNP D0) binds and destabilizes mRNA	Rattus norvegicus
Attenuation phase	Rattus norvegicus
HSF1-dependent transactivation	Rattus norvegicus
HSP90 chaperone cycle for SHRs	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus
PKR-mediated signaling	Rattus norvegicus
Regulation of HSF1-mediated heat shock response	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements