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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Monocyte differentiation antigen CD14
Summary
- UniProt ID
- P10810
- Gene Symbol
-
- Cd14
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003339
- GlyGen
- P10810
- PubChem
- P10810
- The Human Metabolome Database
- HMDBP13786
- RaftProt
- P10810
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- GPI-anchor
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi apparatus |
| external side of plasma membrane |
| cell surface |
| extracellular space |
| membrane raft |
| lipopolysaccharide receptor complex |
| GO Term |
|---|
| lipopolysaccharide binding |
| lipopolysaccharide immune receptor activity |
| lipoteichoic acid binding |
Sequence
MERVLGLLLLLLVHASPAPPEPCELDEESCSCNFSDPKPDWSSAFNCLGAADVELYGGGRSLEYLLKRVDTEADLGQFTDIIKSLSLKRLTVRAARIPSRILFGALRVLGISGLQELTLENLEVTGTAPPPLLEATGPDLNILNLRNVSWATRDAWLAELQQWLKPGLKVLSIAQAHSLNFSCEQVRVFPALSTLDLSDNPELGERGLISALCPLKFPTLQVLALRNAGMETPSGVCSALAAARVQLQGLDLSHNSLRDAAGAPSCDWPSQLNSLNLSFTGLKQVPKGLPAKLSVLDLSYNRLDRNPSPDELPQVGNLSLKGNPFLDSESHSEKFNSGVVTAGAPSSQAVALSGTLALLLGDRLFV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 33 | N-linked (GlcNAc...) asparagine |
|
||
| 147 | N-linked (GlcNAc...) asparagine | |||
| 180 | N-linked (GlcNAc...) asparagine | |||
| 276 | N-linked (GlcNAc...) asparagine |
|
||
| 317 | N-linked (GlcNAc...) asparagine |
G41247ZX
G40574BA
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | Mus musculus |
| IKK complex recruitment mediated by RIP1 | Mus musculus |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Mus musculus |
| Ligand-dependent caspase activation | Mus musculus |
| MyD88-independent TLR4 cascade | Mus musculus |
| Neutrophil degranulation | Mus musculus |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | Mus musculus |
| Regulation of TLR by endogenous ligand | Mus musculus |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | Mus musculus |
| TRIF-mediated programmed cell death | Mus musculus |
