Perforin-1
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| membrane |
| cytoplasmic vesicle |
| cytosol |
| cytolytic granule |
| endosome lumen |
| immunological synapse |
| GO Term |
|---|
| calcium ion binding |
| pore-forming activity |
| wide pore channel activity |
| identical protein binding |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110922 | familial hemophagocytic lymphohistiocytosis 2 | |
| DOID:2377 | multiple sclerosis | |
| DOID:9744 | type 1 diabetes mellitus |
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Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025