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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mannose-binding protein C
Summary
- UniProt ID
- P11226
- Gene Symbol
-
- MBL2
- COLEC1
- MBL
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P11226
- PubChem
- P11226
- The Human Metabolome Database
- HMDBP02647
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Coiled coil
- Collagen
- Complement activation lectin pathway
- Complement pathway
- Direct protein sequencing
- Disulfide bond
- Hydroxylation
- Mannose-binding
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| collagen trimer |
| extracellular space |
| multivesicular body |
| external side of plasma membrane |
| cell surface |
| serine-type endopeptidase complex |
| GO Term |
|---|
| mannose binding |
| calcium-dependent protein binding |
| identical protein binding |
| signaling receptor binding |
Sequence
MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSHLAVCEFPI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 171 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Initial triggering of complement | Homo sapiens |
| Lectin pathway of complement activation | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060538 | purpura fulminans | |
| DOID:0060592 | B-cell adult acute lymphocytic leukemia | |
| DOID:0060851 | pemphigus vulgaris | |
| DOID:0070247 | autosomal dominant Emery-Dreifuss muscular dystrophy 2 | |
| DOID:0080092 | myofibrillar myopathy 1 | |
| DOID:0080094 | myofibrillar myopathy 3 | |
| DOID:0080146 | childhood B-cell acute lymphoblastic leukemia | |
| DOID:0080147 | lymphoblastic lymphoma | |
| DOID:0080159 | Cryptococcal meningitis | |
| DOID:0080162 | lupus nephritis |
