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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Summary
- UniProt ID
- P11310
- Gene Symbol
-
- ACADM
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Direct protein sequencing
- Disease variant
- FAD
- Fatty acid metabolism
- Mitochondrion
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Transit peptide
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| mitochondrial matrix |
| mitochondrial membrane |
| nucleus |
| cytoplasm |
| axon |
| GO Term |
|---|
| flavin adenine dinucleotide binding |
| identical protein binding |
| acyl-CoA dehydrogenase activity |
| medium-chain-acyl-CoA dehydrogenase activity |
Sequence
MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYKN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 280 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA | Homo sapiens |
| Beta oxidation of octanoyl-CoA to hexanoyl-CoA | Homo sapiens |
| PPARA activates gene expression | Homo sapiens |
| mitochondrial fatty acid beta-oxidation of unsaturated fatty acids | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050646 | distal arthrogryposis | |
| DOID:0060262 | gallbladder disease | |
| DOID:0080153 | medium chain acyl-CoA dehydrogenase deficiency | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0090031 | D-bifunctional protein deficiency | |
| DOID:0090129 | carnitine palmitoyltransferase I deficiency | |
| DOID:0111040 | glycogen storage disease IXd |
