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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 1
Summary
- UniProt ID
- P11362
- Gene Symbol
-
- FGFR1
- BFGFR
- CEK
- FGFBR
- FLG
- FLT2
- HBGFR
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011489
- GlyConnect
- GlyGen
- P11362
- PubChem
- P11362
- The Human Metabolome Database
- HMDBP01450
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell membrane
- Chromosomal rearrangement
- Craniosynostosis
- Cytoplasm
- Cytoplasmic vesicle
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Dwarfism
- Glycoprotein
- Heparin-binding
- Holoprosencephaly
- Hypogonadotropic hypogonadism
- Immunoglobulin domain
- Intellectual disability
- Kallmann syndrome
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transcription regulation
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| nucleus |
| plasma membrane |
| membrane |
| cytoplasmic vesicle |
| receptor complex |
| cytosol |
Sequence
MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 77 | N-linked (GlcNAc...) asparagine | |||
| 117 | N-linked (GlcNAc...) asparagine |
|
||
| 227 | N-linked (GlcNAc...) asparagine |
|
||
| 240 | N-linked (GlcNAc...) asparagine |
|
||
| 264 | N-linked (GlcNAc...) asparagine | |||
| 296 | N-linked (GlcNAc...) asparagine | |||
| 317 | N-linked (GlcNAc...) asparagine | |||
| 330 | N-linked (GlcNAc...) asparagine |
|
||
| 586 |
|
|||
| 724 |
|
G62765YT
G08293MJ
G84452RH
G80920RR
G37881RL
G56784JY
G22310AV
G59536GA
G00912UN
G48414YA
G83460ZZ
G59626AS
G70101JE
G47518TP
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | Homo sapiens |
| Formation of paraxial mesoderm | Homo sapiens |
| Signaling by FGFR1 in disease | Homo sapiens |
| Signaling by activated point mutants of FGFR1 | Homo sapiens |
| Signaling by plasma membrane FGFR1 fusions | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
