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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glucose-6-phosphate 1-dehydrogenase
Summary
- UniProt ID
- P11413
- Gene Symbol
-
- G6PD
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Glucose metabolism
- Hereditary hemolytic anemia
- Hydroxylation
- Membrane
- NADP
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| membrane |
| intracellular membrane-bounded organelle |
| extracellular exosome |
| cytosol |
| cytoplasmic side of plasma membrane |
| centriolar satellite |
| cytoplasm |
| GO Term |
|---|
| NADP binding |
| identical protein binding |
| protein homodimerization activity |
| glucose-6-phosphate dehydrogenase activity |
| glucose binding |
Sequence
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 84 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| NFE2L2 regulates pentose phosphate pathway genes | Homo sapiens |
| Pentose phosphate pathway | Homo sapiens |
| TP53 Regulates Metabolic Genes | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0002116 | pterygium | |
| DOID:0014667 | disease of metabolism | |
| DOID:0040085 | bacterial sepsis | |
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:13580 | cholestasis | |
| DOID:0050424 | familial adenomatous polyposis | |
| DOID:0050572 | cone-rod dystrophy | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050771 | pheochromocytoma |
