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Heat shock protein HSP 90-beta

Summary

UniProt ID

P11499

Gene Symbol

Hsp90ab1
Hsp84
Hsp84-1
Hspc3
Hspcb

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003350
GlyGen: P11499
PubChem: P11499
The Human Metabolome Database: HMDBP14552
The O-GlcNAc Database: P11499
RaftProt: P11499
O-GlcNAcAtlas: P11499

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Cell membrane
Chaperone
Cytoplasm
Direct protein sequencing
Glycoprotein
Methylation
Nucleus
Phosphoprotein
Reference proteome
S-nitrosylation
Secreted
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
placenta development
response to organic substance
regulation of cell cycle
supramolecular fiber organization
regulation of protein localization
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
negative regulation of protein metabolic process

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GO Term
extracellular region
nucleus
cytoplasm
lysosomal membrane
plasma membrane
protein-containing complex
melanosome
neuronal cell body
ooplasm
HSP90-CDC37 chaperone complex

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GO Term
nitric-oxide synthase regulator activity
TPR domain binding
heat shock protein binding
ubiquitin protein ligase binding
protein homodimerization activity
ATP-dependent protein binding
protein folding chaperone
protein dimerization activity
tau protein binding
unfolded protein binding

Annotation information from UniProt.

Sequence

MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRMEEVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
46				GlycoProtDB
283			G80920RR	GlyGen
389			G80920RR	GlyGen
434	O-linked (GlcNAc) serine	22556278	G49108TO	UniProt GlyGen The O-GlcNAc Database
452	O-linked (GlcNAc) serine	22556278	G49108TO	UniProt GlyGen The O-GlcNAc Database
462			G49108TO	GlyGen The O-GlcNAc Database
614			G02815KT	GlyGen
			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Aryl hydrocarbon receptor signalling	Mus musculus
Attenuation phase	Mus musculus
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Mus musculus
ESR-mediated signaling	Mus musculus
Estrogen-dependent gene expression	Mus musculus
HSF1 activation	Mus musculus
HSF1-dependent transactivation	Mus musculus
HSP90 chaperone cycle for SHRs	Mus musculus
Neutrophil degranulation	Mus musculus
RHOBTB2 GTPase cycle	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Annotation

International Collaboration

Acknowledgements