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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ribose-phosphate pyrophosphokinase 2
Summary
- UniProt ID
- P11908
- Gene Symbol
-
- PRPS2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P11908
- PubChem
- P11908
- The Human Metabolome Database
- HMDBP00632
- The O-GlcNAc Database
- P11908
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Direct protein sequencing
- Kinase
- Magnesium
- Metal-binding
- Nucleotide biosynthesis
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| cytosol |
| ribose phosphate diphosphokinase complex |
| GO Term |
|---|
| identical protein binding |
| protein homodimerization activity |
| ribose phosphate diphosphokinase activity |
| magnesium ion binding |
| ATP binding |
| kinase activity |
Sequence
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 272 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PRPP biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050457 | Sertoli cell-only syndrome | |
| DOID:0070186 | Y-linked spermatogenic failure 1 | |
| DOID:0070189 | X-linked spermatogenic failure 1 | |
| DOID:14228 | oligospermia | |
| DOID:162 | cancer | |
| DOID:4766 | embryoma | |
| DOID:9074 | systemic lupus erythematosus |
