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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Amyloid-beta precursor protein
Summary
- UniProt ID
- P12023
- Gene Symbol
-
- App
- A4
- AD1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003366
- GlyGen
- P12023
- PubChem
- P12023
- RaftProt
- P12023
- O-GlcNAcAtlas
- P12023
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Amyloid
- Apoptosis
- Cell adhesion
- Cell membrane
- Cell projection
- Coated pit
- Copper
- Cytoplasm
- Cytoplasmic vesicle
- Disulfide bond
- Endocytosis
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Heparin-binding
- Iron
- Isopeptide bond
- Metal-binding
- Notch signaling pathway
- Nucleus
- Phosphoprotein
- Reference proteome
- Secreted
- Serine protease inhibitor
- Signal
- Sulfation
- Transmembrane helix
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| membrane raft |
| recycling endosome |
| nuclear envelope lumen |
| main axon |
| growth cone lamellipodium |
| growth cone filopodium |
| clathrin-coated pit |
| synaptic vesicle |
| presynaptic active zone |
| neuronal dense core vesicle |
| GO Term |
|---|
| signaling receptor binding |
| heparin binding |
Sequence
MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEEEADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVSTQSLLKTTSEPLPQDPDKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Glycosylation Sites
G41247ZX
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| TAK1-dependent IKK and NF-kappa-B activation | Mus musculus |
| TRAF6 mediated NF-kB activation | Mus musculus |
