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Angiotensin-converting enzyme

Summary

UniProt ID

P12821

Gene Symbol

ACE
DCP
DCP1

Organism

Homo sapiens (human)

External Links

GlyConnect

1011

GlyGen

P12821

PubChem

P12821

The Human Metabolome Database

HMDBP01710

Annotation

Keyword

3D-structure
Alternative promoter usage
Alternative splicing
Calmodulin-binding
Carboxypeptidase
Cell membrane
Cytoplasm
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Zinc

Gene Ontology (GO)

Displaying entries **1 - 10** of 56 in total

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GO Term
hormone catabolic process
proteolysis
spermatogenesis
female pregnancy
regulation of blood pressure
embryo development ending in birth or egg hatching
post-transcriptional regulation of gene expression
negative regulation of gene expression
response to nutrient levels
mononuclear cell proliferation

Displaying **all 10** entries
GO Term
extracellular exosome
sperm midpiece
endosome
external side of plasma membrane
basal plasma membrane
extracellular region
extracellular space
lysosome
plasma membrane
brush border membrane

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GO Term
mitogen-activated protein kinase binding
metallodipeptidase activity
exopeptidase activity
heterocyclic compound binding
actin binding
endopeptidase activity
carboxypeptidase activity
metalloendopeptidase activity
calmodulin binding
peptidase activity

Site Annotations

Displaying **all 2** entries
Position	Description
523	Not glycosylated
1225	Not glycosylated

Annotation information from UniProt.

Sequence

MGAASGRRGPGLLLPLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSEVELRHS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 23 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine	20826823 9013598		UniProt GlyGen
54	N-linked (GlcNAc...) asparagine	16476442 20826823 9013598		UniProt GlyGen
74	N-linked (GlcNAc...) asparagine	16476442 20826823 26403559		UniProt GlyGen
103	N-linked (GlcNAc...) asparagine	21810173 24297181 8626443		UniProt
111	N-linked (GlcNAc...) asparagine	19159218 20826823 9013598	G53075ES G05962QB G30740WO G70232NH G55132BD G69521XL G35541EV G13131HA G49755GI G16125XL G68490OW G86880BF G28622IK G80479JV G85282JO G87123QX G79666IR G92135MA G98611JV G02528FI G45395BF G07246CJ G10819WX G40926MX G14972EH G43223CG G49906RN G70441OD G87661QW G83646BJ G60033FS G41071NU G07755XJ G70619PT G65184UU G42124LM G62765YT	UniProt GlyGen
121	N-linked (GlcNAc...) asparagine	8626443		UniProt
140	N-linked (GlcNAc...) asparagine	21810173 24297181 8626443		UniProt
146	N-linked (GlcNAc...) asparagine	16476442 20826823 9013598	G88619MM G10019LZ G11629QQ G07246CJ G82830MN G48414YA G49906RN G27058EU G41071NU G65184UU G42124LM G90659AW G72790NZ	UniProt GlyGen GlyConnect
160	N-linked (GlcNAc...) asparagine	20826823		UniProt GlyGen
318	N-linked (GlcNAc...) asparagine	16476442		UniProt GlyGen