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Interleukin-1 receptor type 1

Summary

UniProt ID

P13504

Gene Symbol

Il1r1
Il-1r1
Il1ra

Organism

Mus musculus (house mouse)

External Links

PubChem: P13504

Annotation

Keyword

Alternative promoter usage
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Hydrolase
Immunoglobulin domain
Inflammatory response
NAD
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
inflammatory response
cytokine-mediated signaling pathway
regulation of inflammatory response
positive regulation of type II interferon production
positive regulation of T-helper 1 cell cytokine production
positive regulation of neuron migration
positive regulation of neutrophil extravasation
positive regulation of interleukin-1-mediated signaling pathway
interleukin-1-mediated signaling pathway
heat acclimation

Displaying **all 5** entries
GO Term
external side of plasma membrane
cell surface
extracellular space
axon
protein-containing complex

Displaying **all 8** entries
GO Term
protease binding
NAD+ nucleotidase, cyclic ADP-ribose generating
NAD+ nucleosidase activity
interleukin-1 receptor activity
interleukin-1, type I, activating receptor activity
interleukin-1 binding
platelet-derived growth factor receptor binding
ionotropic glutamate receptor binding

Annotation information from UniProt.

Sequence

MENMKVLLGLICLMVPLLSLEIDVCTEYPNQIVLFLSVNEIDIRKCPLTPNKMHGDTIIWYKNDSKTPISADRDSRIHQQNEHLWFVPAKVEDSGYYYCIVRNSTYCLKTKVTVTVLENDPGLCYSTQATFPQRLHIAGDGSLVCPYVSYFKDENNELPEVQWYKNCKPLLLDNVSFFGVKDKLLVRNVAEEHRGDYICRMSYTFRGKQYPVTRVIQFITIDENKRDRPVILSPRNETIEADPGSMIQLICNVTGQFSDLVYWKWNGSEIEWNDPFLAEDYQFVEHPSTKRKYTLITTLNISEVKSQFYRYPFICVVKNTNIFESAHVQLIYPVPDFKNYLIGGFIILTATIVCCVCIYKVFKVDIVLWYRDSCSGFLPSKASDGKTYDAYILYPKTLGEGSFSDLDTFVFKLLPEVLEGQFGYKLFIYGRDDYVGEDTIEVTNENVKKSRRLIIILVRDMGGFSWLGQSSEEQIAIYNALIQEGIKIVLLELEKIQDYEKMPDSIQFIKQKHGVICWSGDFQERPQSAKTRFWKNLRYQMPAQRRSPLSKHRLLTLDPVRDTKEKLPAATHLPLG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
63	N-linked (GlcNAc...) asparagine	UniProt
103	N-linked (GlcNAc...) asparagine	UniProt
174	N-linked (GlcNAc...) asparagine	UniProt
236	N-linked (GlcNAc...) asparagine	UniProt
252	N-linked (GlcNAc...) asparagine	UniProt
266	N-linked (GlcNAc...) asparagine	UniProt
300	N-linked (GlcNAc...) asparagine	UniProt