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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Farnesyl pyrophosphate synthase
Summary
- UniProt ID
- P14324
- Gene Symbol
-
- FDPS
- FPS
- KIAA1293
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cholesterol biosynthesis
- Cytoplasm
- Disease variant
- Host-virus interaction
- Hydroxylation
- Isoprene biosynthesis
- Magnesium
- Metal-binding
- Reference proteome
- Transferase
- Gene Ontology (GO)
| GO Term |
|---|
| cholesterol biosynthetic process |
| farnesyl diphosphate biosynthetic process |
| geranyl diphosphate biosynthetic process |
| GO Term |
|---|
| cytoplasm |
| cytosol |
| nucleoplasm |
| GO Term |
|---|
| RNA binding |
| metal ion binding |
| dimethylallyltranstransferase activity |
| geranyltranstransferase activity |
Sequence
MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 4 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of gene expression by SREBF (SREBP) | Homo sapiens |
| Cholesterol biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050819 | obsolete Matthew-Wood syndrome | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060180 | colitis | |
| DOID:0060189 | ileitis | |
| DOID:0060190 | ileocolitis | |
| DOID:0060281 | photosensitive epilepsy | |
| DOID:0080001 | bone disease | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0080522 | thyroid gland anaplastic carcinoma | |
| DOID:0110035 | Alzheimer's disease 2 |
