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Fibrinogen beta chain

Summary

UniProt ID

P14480

Gene Symbol

Ab1-181
Ab1-216
Ac1-581
Fgb

Gene ID

24366

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P14480
PubChem: P14480
Re-Glyco: P14480

Annotation

Keyword

Adaptive immunity
Alternative splicing
Blood coagulation
Coiled coil
Direct protein sequencing
Disulfide bond
Glycoprotein
Innate immunity
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
fibrinogen complex
extracellular space
cell cortex
collagen-containing extracellular matrix
synapse
endoplasmic reticulum
external side of plasma membrane
cell surface
platelet alpha granule
blood microparticle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 21 in total

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GO Term
response to calcium ion
protein-containing complex assembly
positive regulation of ERK1 and ERK2 cascade
cellular response to interleukin-1
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of endothelial cell apoptotic process
positive regulation of heterotypic cell-cell adhesion
positive regulation of vasoconstriction
fibrinolysis
innate immune response

Displaying **all 4** entries
GO Term
cell adhesion molecule binding
protein-folding chaperone binding
signaling receptor binding
structural molecule activity

Annotation information from UniProt.

Sequence

MRHLWLLLLSVSLVQTQAATTDSDKVDLSIARGHRPVDRRKEEPPSLRPAPPPISGGGYRARPAKVDAGQKKVERKPPDAGGCVHGDGDMGVLCPTGCELRQTLLNHERPIKNSIAELNSNINSVSETSSVTFQYLTLLKDMWKKKQAQVKDNENVINEYSSILEDQKLYIDETVNDNIPLNLRVLRSILEDLRSKIQKLESDISAQTEYCHTPCTVNCNIPVVSGKECEEIIRKGGETSEMYLIQPDTSSKPYRVYCDMKTENGGWTVIQNRQDGSVDFGRKWDPYKKGFGNIATNEDTKKYCGLPGEYWLGNDKISQLTRIGPTELLIEMEDWKGDKVKAHYGGFTVQTEANKYQVSVNKYKGTAGNALMEGASQLVGENRTMTIHNGMFFSTYDRDNDGWVTTDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGLYSWDMSKHGTDDGVVWMNWKGSWYSMRRMSMKIRPVFPQQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
382	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Common Pathway of Fibrin Clot Formation	Rattus norvegicus
GRB2:SOS provides linkage to MAPK signaling for Integrins	Rattus norvegicus
Integrin cell surface interactions	Rattus norvegicus
Integrin signaling	Rattus norvegicus
MAP2K and MAPK activation	Rattus norvegicus
Platelet degranulation	Rattus norvegicus
Regulation of TLR by endogenous ligand	Rattus norvegicus
p130Cas linkage to MAPK signaling for integrins	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements