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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phospholipase A2, membrane associated
Summary
- UniProt ID
- P14555
- Gene Symbol
-
- PLA2G2A
- PLA2B
- PLA2L
- RASF-A
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P14555
- PubChem
- P14555
- SwissLipids
- The Human Metabolome Database
- HMDBP00072
Annotation
- Keyword
-
- 3D-structure
- Bacteriolytic enzyme
- Calcium
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Hydrolase
- Inflammatory response
- Metal-binding
- Mitochondrion outer membrane
- Phospholipid metabolism
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| calcium-dependent phospholipase A2 activity |
| phospholipase A2 activity |
| phospholipid binding |
| calcium ion binding |
Sequence
MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Acyl chain remodelling of PC | Homo sapiens |
| Acyl chain remodelling of PE | Homo sapiens |
| Acyl chain remodelling of PG | Homo sapiens |
| Acyl chain remodelling of PI | Homo sapiens |
| Acyl chain remodelling of PS | Homo sapiens |
| Antimicrobial peptides | Homo sapiens |
| Synthesis of PA | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110046 | Alzheimer's disease 13 | |
| DOID:0110047 | Alzheimer's disease 14 | |
| DOID:0110048 | Alzheimer's disease 15 | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111044 | gray platelet syndrome | |
| DOID:0111049 | platelet-type bleeding disorder 17 | |
| DOID:0111051 | platelet-type bleeding disorder 18 | |
| DOID:0111382 | ischiocoxopodopatellar syndrome | |
| DOID:10041 | dysplastic nevus syndrome | |
| DOID:10155 | intestinal cancer |
