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MIRAGE
Lamin-B1
Summary
- UniProt ID
- P14733
- Gene Symbol
-
- Lmnb1
- Gene ID
- 16906
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Coiled coil
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Intermediate filament
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- Prenylation
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| nuclear envelope |
| nucleoplasm |
| nuclear inner membrane |
| nuclear lamina |
| nuclear matrix |
| nuclear periphery |
| lamin filament |
| GO Term |
|---|
| positive regulation of G2/M transition of mitotic cell cycle |
| nuclear envelope organization |
| positive regulation of JNK cascade |
Sequence
MATATPVQQQRAGSRASAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRMLSDREREMAEIRDQMQQQLSDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVAVEEERFHQQGAPRASNKSCAIM
Glycosylation Sites
G49108TO
G39446WN
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Breakdown of the nuclear lamina | Mus musculus |
| Depolymerization of the Nuclear Lamina | Mus musculus |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | Mus musculus |
| Initiation of Nuclear Envelope (NE) Reformation | Mus musculus |
| RHOD GTPase cycle | Mus musculus |
| RHOF GTPase cycle | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060785 | typical adult-onset autosomal dominant demyelinating leukodystrophy |
