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MIRAGE
Interleukin-2 receptor subunit beta
Summary
- UniProt ID
- P14784
- Gene Symbol
-
- IL15RB
- IL2RB
- Gene ID
- 3560
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Host-virus interaction
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| endosome |
| cytosol |
| external side of plasma membrane |
| cell surface |
| interleukin-2 receptor complex |
| plasma membrane |
| membrane |
| GO Term |
|---|
| interleukin-2 receptor activity |
| interleukin-2 binding |
| interleukin-15 receptor activity |
| cytokine receptor activity |
| coreceptor activity |
Sequence
MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 29 | N-linked (GlcNAc...) asparagine |
|
||
| 43 | N-linked (GlcNAc...) asparagine |
|
||
| 71 | N-linked (GlcNAc...) asparagine |
|
||
| 149 | N-linked (GlcNAc...) asparagine | |||
| 476 |
|
|
G74381CZ
G61256FT
G49955PK
G57317CE
G92050GC
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin receptor SHC signaling | Homo sapiens |
| Interleukin-15 signaling | Homo sapiens |
| Interleukin-2 signaling | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111997 | immunodeficiency 63 | |
| DOID:2841 | asthma | |
| DOID:437 | myasthenia gravis | |
| DOID:9146 | visceral leishmaniasis |
