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MIRAGE
Fibroblast growth factor receptor 1

Summary
UniProt ID
P16092
Gene Symbol
  • Fgfr1
  • Flg
Gene ID
14182
Organism
Mus musculus (house mouse)
GlycoProtDB
GPDB0003422
GlyConnect
GlyGen
P16092
PubChem
P16092
The O-GlcNAc Database
P16092
Re-Glyco
P16092
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Cell membrane
  • Cytoplasm
  • Cytoplasmic vesicle
  • Disulfide bond
  • Glycoprotein
  • Heparin-binding
  • Immunoglobulin domain
  • Nucleus
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
  • Ubl conjugation
Gene Ontology (GO)
Displaying all 7 entries
GO Term
glutamatergic synapse
plasma membrane
cytoplasmic vesicle
receptor complex
postsynapse
cytosol
nucleus
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MWGWKCLLFWAVLVTATLCTARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDDVQSINWLRDGVQLVESNRTRITGEEVEVRDSIPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMLGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSIPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPTQLANSGLKRR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 10 entries
Position Description PubMed ID GlyTouCan ID Source
76
77 N-linked (GlcNAc...) asparagine
117 N-linked (GlcNAc...) asparagine
227 N-linked (GlcNAc...) asparagine
240 N-linked (GlcNAc...) asparagine
264 N-linked (GlcNAc...) asparagine
296 N-linked (GlcNAc...) asparagine
317 N-linked (GlcNAc...) asparagine
330 N-linked (GlcNAc...) asparagine
724
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 14 in total
Pathway Name Organism
Downstream signaling of activated FGFR1 Mus musculus
FGFR1b ligand binding and activation Mus musculus
FGFR1c and Klotho ligand binding and activation Mus musculus
FGFR1c ligand binding and activation Mus musculus
FRS-mediated FGFR1 signaling Mus musculus
Negative regulation of FGFR1 signaling Mus musculus
PI-3K cascade:FGFR1 Mus musculus
PI3K Cascade Mus musculus
PI3K/AKT Signaling Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Mus musculus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025