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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
P-selectin
Summary
- UniProt ID
- P16109
- Gene Symbol
-
- SELP
- GMRP
- GRMP
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P16109
- PubChem
- P16109
- The Human Metabolome Database
- HMDBP02132
- RaftProt
- P16109
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell adhesion
- Cell membrane
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Lectin
- Metal-binding
- Palmitate
- Reference proteome
- Repeat
- Signal
- Sushi
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| platelet dense granule membrane |
| platelet alpha granule membrane |
| external side of plasma membrane |
| extracellular space |
| plasma membrane |
Sequence
MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 54 | N-linked (GlcNAc...) asparagine | |||
| 98 | N-linked (GlcNAc...) asparagine |
|
||
| 180 | N-linked (GlcNAc...) asparagine |
|
||
| 212 | N-linked (GlcNAc...) asparagine |
|
||
| 219 | N-linked (GlcNAc...) asparagine |
|
||
| 272 |
|
|||
| 411 | N-linked (GlcNAc...) asparagine | |||
| 460 | N-linked (GlcNAc...) asparagine | |||
| 518 | N-linked (GlcNAc...) asparagine |
|
||
| 665 | N-linked (GlcNAc...) asparagine |
|
G27058EU
G57888GL
G48414YA
G84452RH
G70232NH
G22310AV
G45395BF
G64394MX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
| Platelet degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110760 | type 1 diabetes mellitus 23 | |
| DOID:0110761 | type 1 diabetes mellitus 24 | |
| DOID:0111044 | gray platelet syndrome | |
| DOID:0111049 | platelet-type bleeding disorder 17 | |
| DOID:0111051 | platelet-type bleeding disorder 18 | |
| DOID:0111054 | von Willebrand's disease 3 | |
| DOID:10127 | cerebral artery occlusion | |
| DOID:10459 | common cold | |
| DOID:10460 | nasopharyngitis | |
| DOID:1074 | kidney failure |
