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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Summary
- UniProt ID
- P16393
- Gene Symbol
-
- HMGCR
- Organism
- Strongylocentrotus purpuratus (purple sea urchin)
External Links
Annotation
- Keyword
-
- Cholesterol biosynthesis
- Endoplasmic reticulum
- Glycoprotein
- NADP
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cholesterol biosynthetic process |
| isoprenoid biosynthetic process |
| coenzyme A metabolic process |
| sterol biosynthetic process |
| GO Term |
|---|
| endoplasmic reticulum membrane |
| peroxisomal membrane |
| GO Term |
|---|
| hydroxymethylglutaryl-CoA reductase (NADPH) activity |
| NADP binding |
Sequence
MLSRLFLAQGRFCSSHPWEVIVCTLTLTICMLSMNYFTGLPRICGWNYECAPQVKESSLSSDVLVMCIMRTLAVAYLYLQFTKLRTTGSKYILGIAGLFTIFSSFLFSSAVIHLFGLELTGLNEALPFFLLLIDLTKASALTKFALSSTTQNEVVDNIARGMAILGPTITLDTVVTTLVISIGTMSSIRKMEVFCCFGILSLIANYFVFMTFFPACLSLVLELSNSNKYGRPVWHLGRFAEVLEEEEDRKPNPVVQRVKMIMRTGLVLVHAHSYWLASNDTELMSRDMLYDGNLLTDKKIDPTMPLWEFYATRLWPPTLDYILTAILATVLASHYIFFSDLATYPEKRVSIMEGHEVVNPGSDHEDASEVETIGTLSSSPSTSDVRVIESMTSRTQACQTDPVTASPRNSRSSSPVSSHSVKPARFTIGSSGSGSEDEEEEVIKEEEVEWVLETELKAPRPMPELLEILNVGKGPNALTDDEVQLLVGAKHIPAYKLENILDNPERGVAVRRQIISKLLPITDALEKLPYASYDYSFVSGACCENVIGYMPVPVGVAGPLLLDGQEFQVPMATTEGCLVASTNRGCRALRSAGGIHSVLIGDGMTRGPLVRLPSAQEAGAIKQWLEVPENFAAIKERFESTSRFAKLKSIQTALAGRYMFLRFKALTGDAMGMNMISKGTEQALHALQTMFPNIEIMSLSGNYCTDKKVAAINWIEGRGKSVVCEATVPAHIVQQVLKTSASALVDLNIHKNLVGSAMAGSIGGFNAHAANIVTAIYIATGQDAAQNIASSNCMTLMETRGPKGGDLYLSCTMPSIELGTVGGGTVLPPQSACLQMMDVKGSNIHGSGLNASQLARIVCATVMAGELSLMSALAAGHLVKSHMKHNRSALNIASPLPSIDEVATHRRSKSVDFSALKESSAAAPGTCTANAS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
