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Dipeptidase 1

Summary

UniProt ID

P16444

Gene Symbol

DPEP1
MDP
RDP

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011574

GlyConnect

1174

GlyGen

P16444

PubChem

P16444

The Human Metabolome Database

HMDBP02684

The O-GlcNAc Database

P16444

RaftProt

P16444

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Dipeptidase
Direct protein sequencing
Disulfide bond
GPI-anchor
Lipid metabolism
Metal-binding
Metalloprotease
Reference proteome
Signal
Zinc

Gene Ontology (GO)

Displaying entries **11 - 15** of 15 in total

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GO Term
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
glutathione catabolic process
cellular response to xenobiotic stimulus
lactam catabolic process
leukotriene D4 catabolic process

Displaying **all 9** entries
GO Term
extracellular space
plasma membrane
cell junction
extracellular exosome
apical plasma membrane
microvillus membrane
apical part of cell
nucleoplasm
side of membrane

Displaying **all 8** entries
GO Term
modified amino acid binding
dipeptidase activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
metalloexopeptidase activity
GPI anchor binding
zinc ion binding
beta-lactamase activity
metallodipeptidase activity

Annotation information from UniProt.

Sequence

MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAVEQASNLTQAPEEEPIPLDQLGGSCRTHYGYSSGASSLHRHWGLLLASLAPLVLCLSLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
57	N-linked (GlcNAc...) asparagine	12144777 19159218	G63040RU G53075ES G07810QS G71463BG G82443XX G01160VV G60967DT G30740WO G78649WQ G12341GU G70232NH G55132BD G69521XL G06247RL G35541EV G93718GY G13131HA G49755GI G80075MS G29545VG G68490OW G77669RF G60834IK G86880BF G27947YN G28622IK G90382BL G80479JV G85282JO G40206WX G20528HD G87123QX G79666IR G92135MA G98611JV G40834TG G02528FI G43669FQ G45395BF G59324HL G07246CJ G85554PZ G10819WX G40926MX G14972EH G43223CG G58954YZ G37412TK G78787DI G08918WF G00912UN G49906RN G58087IP G27915IV G87389XI G61256FT G70441OD G87661QW G83646BJ G76295SF G04657PL G27058EU G51653BI G85582CB G83460ZZ G70223PD G10488MI G41071NU G07755XJ G86182NS G35253PZ G72747WU G70619PT G59626AS G41840AI G80920RR G47702MW G01485JJ G65184UU G42124LM G90659AW G77547TA G45504EY G62765YT G72790NZ G10486CT G05049YU G28541PG G31852PQ G72787SB G23719VF G39446WN G35029YA G36379GD G37995HC	UniProt GlyGen
66			G49108TO	GlyGen The O-GlcNAc Database
279	N-linked (GlcNAc...) asparagine	19159218	G89827JR G12341GU G69521XL G35541EV G13131HA G49755GI G80075MS G57776ZS G16125XL G68490OW G60834IK G86880BF G27947YN G80479JV G85282JO G20528HD G79666IR G92135MA G43669FQ G45395BF G07246CJ G85554PZ G10819WX G40926MX G14972EH G43223CG G00273SJ G08918WF G00912UN G49906RN G27915IV G70441OD G87661QW G83646BJ G04657PL G27058EU G24528MX G85582CB G43769HG G83460ZZ G60033FS G41071NU G07755XJ G86182NS G72747WU G70619PT G59626AS G46503DX G80920RR G63041LO G65184UU G42124LM G90659AW G29299MO G37399XV G62765YT G72790NZ G10486CT G05049YU G18647XP G72787SB G89045VA	UniProt GlyGen
332	N-linked (GlcNAc...) asparagine	12144777	G12745LE G94665LC G89827JR G15127JD G30221QT G71463BG G82443XX G32788FZ G56518TU G01160VV G60967DT G80669SJ G39471UU G30740WO G78649WQ G70232NH G55132BD G69521XL G81124ET G03644CB G35541EV G13131HA G49755GI G80075MS G57776ZS G29545VG G68490OW G60834IK G28622IK G90382BL G80479JV G85282JO G20528HD G87123QX G92135MA G98611JV G45395BF G07246CJ G70375MX G85554PZ G10819WX G14972EH G43223CG G27915IV G87661QW G83646BJ G04657PL G27058EU G51653BI G83460ZZ G37509XX G41071NU G07755XJ G80920RR G42124LM G77547TA G45504EY G62765YT G50045TK G05049YU G31852PQ G02815KT	GlycoProtDB UniProt GlyGen GlyConnect
358	N-linked (GlcNAc...) asparagine		G89827JR G30221QT G71463BG G65414LI G50856PC G99679NM G82443XX G95046LV G32788FZ G01160VV G60967DT G80669SJ G39471UU G05962QB G30740WO G45526EA G12341GU G55132BD G37818NZ G69521XL G81124ET G03644CB G49589RB G35541EV G93718GY G13131HA G49755GI G75568BH G80075MS G57776ZS G16125XL G29545VG G44753VC G68490OW G99668VU G60834IK G86880BF G27947YN G28622IK G90382BL G80479JV G85282JO G20528HD G37692EO G33416PL G87123QX G79666IR G92135MA G98611JV G40834TG G02528FI G43669FQ G45395BF G59324HL G07246CJ G10819WX G40926MX G14972EH G43223CG G58954YZ G00273SJ G08918WF G49906RN G27915IV G70441OD G87661QW G83646BJ G36442WJ G17208MA G76295SF G46691LC G27126ED G04657PL G27058EU G85582CB G83460ZZ G37509XX G70223PD G60033FS G41071NU G07755XJ G86182NS G46503DX G80920RR G01485JJ G65184UU G42124LM G62765YT G72790NZ G05049YU G31852PQ G37995HC G84225JN	UniProt GlyGen
360			G43417UB	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Aflatoxin activation and detoxification	Homo sapiens
LTC4-CYSLTR mediated IL4 production	Homo sapiens
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Homo sapiens

Human Protein Atlas

ENSG00000015413

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Displaying entries **1 - 10** of **142** in total

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DO ID	Disease Name	Source
DOID:0050424	familial adenomatous polyposis	DisGeNET
DOID:0050557	congenital muscular dystrophy	DisGeNET
DOID:0050589	inflammatory bowel disease	DisGeNET DisGeNET
DOID:0050819	obsolete Matthew-Wood syndrome	DisGeNET
DOID:0050835	generalized dystonia	DisGeNET
DOID:0050841	focal hand dystonia	DisGeNET
DOID:0060178	familial hemiplegic migraine	DisGeNET
DOID:0060192	Crohn's colitis	DisGeNET
DOID:0060255	rippling muscle disease 2	DisGeNET
DOID:0060706	X-linked lymphoproliferative syndrome 2	DisGeNET

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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External Links

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Acknowledgements