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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Vascular endothelial growth factor A
Summary
- UniProt ID
- P16612
- Gene Symbol
-
- Vegfa
- Vegf
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P16612
Annotation
- Keyword
-
- Alternative splicing
- Angiogenesis
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Heparin-binding
- Mitogen
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| vasodilation |
| apoptotic process |
| nervous system development |
| neuroblast proliferation |
| mesoderm development |
| female pregnancy |
| lactation |
| cell population proliferation |
| positive regulation of cell population proliferation |
| positive regulation of signal transduction |
| GO Term |
|---|
| VEGF-A complex |
| adherens junction |
| membrane |
| secretory granule |
| vesicle |
| extracellular region |
| basement membrane |
| extracellular space |
| nucleus |
| cytoplasm |
| GO Term |
|---|
| growth factor binding |
| chemoattractant activity |
| heparin binding |
Sequence
MNFLLSWVHWTLALLLYLHHAKWSQAAPTTEGEQKAHEVVKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNVTMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPEKKSVRGKGKGQKRKRKKSRFKSWSVHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 100 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Platelet degranulation | Rattus norvegicus |
| VEGF binds to VEGFR leading to receptor dimerization | Rattus norvegicus |
| VEGF ligand-receptor interactions | Rattus norvegicus |
| VEGFA-VEGFR2 Pathway | Rattus norvegicus |
| VEGFR2 mediated cell proliferation | Rattus norvegicus |
