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Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

Summary

UniProt ID

P16615

Gene Symbol

ATP2A2
ATP2B

Organism

Homo sapiens (human)

External Links

GlyGen: P16615
PubChem: P16615
The Human Metabolome Database: HMDBP01470
The O-GlcNAc Database: P16615
RaftProt: P16615

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Calcium transport
Disease variant
Disulfide bond
Endoplasmic reticulum
Epilepsy
Magnesium
Metal-binding
Nitration
Phosphoprotein
Reference proteome
Sarcoplasmic reticulum
Translocase
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 32 in total

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GO Term
autophagosome assembly
intracellular calcium ion homeostasis
cell adhesion
epidermis development
positive regulation of cardiac muscle cell apoptotic process
regulation of cardiac muscle contraction by calcium ion signaling
monoatomic ion transmembrane transport
cellular response to oxidative stress
negative regulation of heart contraction
neuron cellular homeostasis

Displaying **all 10** entries
GO Term
platelet dense tubular network membrane
endoplasmic reticulum
endoplasmic reticulum membrane
longitudinal sarcoplasmic reticulum
sarcoplasmic reticulum
sarcoplasmic reticulum membrane
calcium ion-transporting ATPase complex
ribbon synapse
plasma membrane
membrane

Displaying **all 9** entries
GO Term
S100 protein binding
ATP hydrolysis activity
transmembrane transporter binding
P-type calcium transporter activity
ATP binding
P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential
lncRNA binding
calcium ion binding
enzyme binding

Annotation information from UniProt.

Sequence

MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Ion homeostasis	Homo sapiens
Ion transport by P-type ATPases	Homo sapiens
Pre-NOTCH Processing in Golgi	Homo sapiens
Reduction of cytosolic Ca++ levels	Homo sapiens

Human Protein Atlas

ENSG00000174437

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements