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Polypyrimidine tract-binding protein 1

Summary

UniProt ID

P17225

Gene Symbol

Ptbp1
Ptb

Organism

Mus musculus (house mouse)

External Links

GlyGen: P17225
PubChem: P17225
The O-GlcNAc Database: P17225
RaftProt: P17225

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Repeat
Repressor
Ubl conjugation
mRNA splicing

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

1

2

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GO Term
mRNA processing
negative regulation of mRNA splicing, via spliceosome
gene expression
positive regulation of neuron projection development
neurogenesis
positive regulation of insulin secretion
regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of translation
negative regulation of muscle cell differentiation

Displaying **all 2** entries
GO Term
neuron projection terminus
nucleus

Displaying **all 6** entries
GO Term
RNA binding
sequence-specific DNA binding
single-stranded DNA endodeoxyribonuclease activity
regulatory region RNA binding
single-stranded DNA binding
mRNA binding

Annotation information from UniProt.

Sequence

MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSSSASAANGNDSKKFKGDNRSAGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAASRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites