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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Sphingomyelin phosphodiesterase
Summary
- UniProt ID
- P17405
- Gene Symbol
-
- SMPD1
- ASM
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P17405
- PubChem
- P17405
- SwissLipids
- The Human Metabolome Database
- HMDBP00776
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Glycosidase
- Host-virus interaction
- Lipid droplet
- Lipid metabolism
- Lysosome
- Metal-binding
- Neurodegeneration
- Niemann-Pick disease
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| response to type I interferon |
| cellular response to UV |
| positive regulation of protein dephosphorylation |
| negative regulation of MAP kinase activity |
| response to interleukin-1 |
| GO Term |
|---|
| endosome |
| extracellular space |
| lysosome |
| plasma membrane |
| lipid droplet |
| endolysosome |
| lamellar body |
| lysosomal lumen |
| extracellular exosome |
Sequence
MPRYGASLRQSCPRSGREQGQDGTAGAPGLLWMGLVLALALALALALALSDSRVLWAPAEAHPLSPQGHPARLHRIVPRLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGHWDIFSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPAGPFDMVYWTGDIPAHDVWHQTRQDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNSFPPPFIEGNHSSRWLYEAMAKAWEPWLPAEALRTLRIGGFYALSPYPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPGHCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETLSRPLAVAFLAPSATTYIGLNPGYRVYQIDGNYSGSSHVVLDHETYILNLTQANIPGAIPHWQLLYRARETYGLPNTLPTAWHNLVYRMRGDMQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALCRHLMPDGSLPEAQSLWPRPLFC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 88 | N-linked (GlcNAc...) asparagine | |||
| 177 | N-linked (GlcNAc...) asparagine |
|
||
| 337 | N-linked (GlcNAc...) asparagine | |||
| 383 |
|
|
||
| 397 | N-linked (GlcNAc...) asparagine |
|
||
| 440 |
|
|
||
| 505 | N-linked (GlcNAc...) asparagine |
|
||
| 522 | N-linked (GlcNAc...) asparagine |
|
G36670VW
G91473PK
G08290VR
G43769HG
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Glycosphingolipid catabolism | Homo sapiens |
