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Leukemia inhibitory factor

Summary

UniProt ID

P17777

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P17777

Annotation

Keyword

Cytokine
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **41 - 49** of 49 in total

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GO Term
positive regulation of transcription by RNA polymerase II
leukemia inhibitory factor signaling pathway
positive regulation of MAPK cascade
receptor signaling pathway via STAT
positive regulation of peptidyl-serine phosphorylation
positive regulation of peptidyl-serine phosphorylation of STAT protein
positive regulation of cell adhesion mediated by integrin
positive regulation of tyrosine phosphorylation of STAT protein
negative regulation of ERK1 and ERK2 cascade

Displaying 1 entry
GO Term
extracellular space

Displaying **all 4** entries
GO Term
cytokine activity
leukemia inhibitory factor receptor binding
growth factor activity
signaling receptor binding

Annotation information from UniProt.

Sequence

MKVLAAGIVPLLLILHWKHGAGSPLPITPVNATCAIRHPCHGNLMNQIKSQLAQLNGSANALFISYYTAQGEPFPNNVDKLCAPNMTDFPPFHANGTEKTKLVELYRMVTYLGASLTNITWDQKNLNPTAVSLQIKLNATTDVMRGLLSSVLCRLCNKYHVGHVDVPCVPDNSSKEAFQRKKLGCQLLGTYKQVISVLAQAF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
31	N-linked (GlcNAc...) asparagine	UniProt
56	N-linked (GlcNAc...) asparagine	UniProt
85	N-linked (GlcNAc...) asparagine	UniProt
95	N-linked (GlcNAc...) asparagine	UniProt
118	N-linked (GlcNAc...) asparagine	UniProt
138	N-linked (GlcNAc...) asparagine	UniProt
172	N-linked (GlcNAc...) asparagine	UniProt