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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cathepsin D
Summary
- UniProt ID
- P18242
- Gene Symbol
-
- Ctsd
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Aspartyl protease
- Disulfide bond
- Glycoprotein
- Lysosome
- Reference proteome
- Secreted
- Signal
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| GABA-ergic synapse |
| melanosome |
| collagen-containing extracellular matrix |
| membrane raft |
| presynaptic endosome |
| lysosomal membrane |
| endosome membrane |
| endosome lumen |
| extracellular space |
| mitochondrion |
| GO Term |
|---|
| hydrolase activity |
| aspartic-type peptidase activity |
| endopeptidase activity |
| aspartic-type endopeptidase activity |
| peptidase activity |
| peptide binding |
Sequence
MKTPGVLLLILGLLASSSFAIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSGPLWILGDVFIGSYYTVFDRDNNRVGFANAVVL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 134 | N-linked (GlcNAc...) asparagine | |||
| 258 |
|
|||
| 261 | N-linked (GlcNAc...) (high mannose) asparagine | |||
| 263 |
|
G05724UK
G39188ZX
G41247ZX
G06110VR
G49108TO
G84820NF
G11870QZ
G93180LE
G25637MV
G00406II
G66538GV
G74724QE
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Collagen degradation | Mus musculus |
| Insulin receptor recycling | Mus musculus |
| MHC class II antigen presentation | Mus musculus |
| Metabolism of Angiotensinogen to Angiotensins | Mus musculus |
| Neutrophil degranulation | Mus musculus |
