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Phosphatidylcholine-sterol acyltransferase

Summary

UniProt ID

P18424

Gene Symbol

Lcat

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem

P18424

SwissLipids

SLP:000001728

Annotation

Keyword

Acyltransferase
Cholesterol metabolism
Disulfide bond
Glycoprotein
Hydrolase
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
lipid metabolic process
lipoprotein metabolic process
lipoprotein biosynthetic process
response to glucocorticoid
reverse cholesterol transport
aflatoxin metabolic process
response to copper ion
phospholipid metabolic process
cholesterol metabolic process
cholesterol homeostasis

Displaying **all 2** entries
GO Term
high-density lipoprotein particle
extracellular space

Displaying **all 6** entries
GO Term
platelet-activating factor acetyltransferase activity
1-alkyl-2-acetylglycerophosphocholine esterase activity
phosphatidylcholine-sterol O-acyltransferase activity
phospholipase A2 activity
sterol esterase activity
apolipoprotein A-I binding

Annotation information from UniProt.

Sequence

MGLPGSPWQWVLLLLGLLLPPATSFWLLNVLFPPHTTPKAELSNHTRPVILVPGCMGNRLEAKLDKPNVVNWLCYRKTEDFFTIWLDFNMFLPLGVDCWIDNTRVVYNRSSGHMSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPRQQDEYYQKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLHFLLRQPQSWKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPIMSNIKLREEQRITTTSPWMFPAHHVWPEDHVFISTPNFNYTGQDFERFFADLHFEEGWHMFLQSRDLLAGLPAPGVEVYCLYGVGMPTAHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQAVHLLPMNGTDHLNMVFSNKTLEHINAILLGAYRHGTPKSPTASLGPPTKE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
44	N-linked (GlcNAc...) asparagine	UniProt
108	N-linked (GlcNAc...) asparagine	UniProt
296	N-linked (GlcNAc...) asparagine	UniProt
397	N-linked (GlcNAc...) asparagine	UniProt
408	N-linked (GlcNAc...) asparagine	UniProt