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MIRAGE
Phosphatidylcholine-sterol acyltransferase

Summary
UniProt ID
P18424
Gene Symbol
  • Lcat
Gene ID
24530
Organism
Rattus norvegicus (Norway rat)
PubChem
P18424
SwissLipids
Re-Glyco
P18424
Annotation
Keyword
  • Acyltransferase
  • Cholesterol metabolism
  • Disulfide bond
  • Glycoprotein
  • Hydrolase
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 2 entries
GO Term
extracellular space
high-density lipoprotein particle
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MGLPGSPWQWVLLLLGLLLPPATSFWLLNVLFPPHTTPKAELSNHTRPVILVPGCMGNRLEAKLDKPNVVNWLCYRKTEDFFTIWLDFNMFLPLGVDCWIDNTRVVYNRSSGHMSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPRQQDEYYQKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLHFLLRQPQSWKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPIMSNIKLREEQRITTTSPWMFPAHHVWPEDHVFISTPNFNYTGQDFERFFADLHFEEGWHMFLQSRDLLAGLPAPGVEVYCLYGVGMPTAHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQAVHLLPMNGTDHLNMVFSNKTLEHINAILLGAYRHGTPKSPTASLGPPTKE
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
44 N-linked (GlcNAc...) asparagine
108 N-linked (GlcNAc...) asparagine
296 N-linked (GlcNAc...) asparagine
397 N-linked (GlcNAc...) asparagine
408 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
HDL remodeling Rattus norvegicus
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:1168 familial hyperlipidemia
DOID:5844 myocardial infarction
DOID:783 end stage renal disease
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025