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Frizzled
Summary
- UniProt ID
- P18537
- Gene Symbol
-
- CG17697
- fz
- Gene ID
- 45307
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Cell membrane
- Developmental protein
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| membrane |
| GO Term |
|---|
| G protein-coupled receptor activity |
| Wnt-protein binding |
| Wnt receptor activity |
Sequence
MWRQILFILPTLIQGVQRYDQSPLDASPYYRSGGGLMASSGTELDGLPHHNRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERPIPPCRSLCESARVCEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKDLHDCGAPCHAMFFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAARAPGSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERLQGKEPRTRAQAYV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of RAC1:GTP by FZ:DSH complex | Drosophila melanogaster |
| Activation of RHO1 by FZ:DSH complex | Drosophila melanogaster |
| Activation of non-muscle Myosin II | Drosophila melanogaster |
| Assembly of receptor complex | Drosophila melanogaster |
| Asymmetric localization of PCP proteins | Drosophila melanogaster |
| Ca2+ pathway | Drosophila melanogaster |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | Drosophila melanogaster |
| Formation and asymmetric localisation of transmembrane complexes | Drosophila melanogaster |
| Homo-/heterophilic binding of transmembrane components | Drosophila melanogaster |
| Inhibition of actin polymerization | Drosophila melanogaster |
