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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Frizzled
Summary
- UniProt ID
- P18537
- Gene Symbol
-
- fz
- Organism
- Drosophila melanogaster (fruit fly)
External Links
- PubChem
- P18537
Annotation
- Keyword
-
- Cell membrane
- Developmental protein
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| membrane |
| GO Term |
|---|
| G protein-coupled receptor activity |
| Wnt-protein binding |
| Wnt receptor activity |
Sequence
MWRQILFILPTLIQGVQRYDQSPLDASPYYRSGGGLMASSGTELDGLPHHNRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERPIPPCRSLCESARVCEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKDLHDCGAPCHAMFFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAARAPGSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERLQGKEPRTRAQAYV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PCP/CE pathway | Drosophila melanogaster |
| Phosphorylation of ARR | Drosophila melanogaster |
| Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM | Drosophila melanogaster |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | Drosophila melanogaster |
