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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Syndecan-1
Summary
- UniProt ID
- P18828
- Gene Symbol
-
- Sdc1
- Synd-1
- Synd1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Heparan sulfate
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of extracellular exosome assembly |
| response to cAMP |
| canonical Wnt signaling pathway |
| receptor-mediated endocytosis |
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| Golgi lumen |
| external side of plasma membrane |
| cell surface |
| protein-containing complex |
| GO Term |
|---|
| cargo receptor activity |
| identical protein binding |
Sequence
MRRAALWLWLCALALRLQPALPQIVAVNVPPEDQDGSGDDSDNFSGSGTGALPDTLSRQTPSTWKDVWLLTATPTAPEPTSSNTETAFTSVLPAGEKPEEGEPVLHVEAEPGFTARDKEKEVTTRPRETVQLPITQRASTVRVTTAQAAVTSHPHGGMQPGLHETSAPTAPGQPDHQPPRVEGGGTSVIKEVVEDGTANQLPAGEGSGEQDFTFETSGENTAVAAVEPGLRNQPPVDEGATGASQSLLDRKEVLGGVIAGGLVGLIFAVCLVAFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 37 | O-linked (Xyl...) (chondroitin sulfate) serine |
|
||
| 43 | N-linked (GlcNAc...) asparagine |
|
||
| 45 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 47 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 207 | O-linked (Xyl...) (chondroitin sulfate) serine |
|
||
| 217 | O-linked (Xyl...) (chondroitin sulfate) serine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Mus musculus |
| Cell surface interactions at the vascular wall | Mus musculus |
| HS-GAG biosynthesis | Mus musculus |
| HS-GAG degradation | Mus musculus |
| Other interleukin signaling | Mus musculus |
| Retinoid metabolism and transport | Mus musculus |
| Syndecan interactions | Mus musculus |
