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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Myeloid cell surface antigen CD33
Summary
- UniProt ID
- P20138
- Gene Symbol
-
- CD33
- SIGLEC3
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P20138
- PubChem
- P20138
- The Human Metabolome Database
- HMDBP14336
- The O-GlcNAc Database
- P20138
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell adhesion
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Lectin
- Peroxisome
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of monocyte activation |
| immune response-inhibiting signal transduction |
| positive regulation of protein tyrosine phosphatase activity |
| GO Term |
|---|
| nucleoplasm |
| external side of plasma membrane |
| cell surface |
| specific granule membrane |
| Golgi apparatus |
| plasma membrane |
| tertiary granule membrane |
| peroxisome |
| GO Term |
|---|
| protein phosphatase binding |
| sialic acid binding |
| signaling receptor activity |
| carbohydrate binding |
Sequence
MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 99 |
|
|
||
| 100 | N-linked (GlcNAc...) asparagine | |||
| 113 | N-linked (GlcNAc...) asparagine |
|
||
| 160 | N-linked (GlcNAc...) asparagine |
|
||
| 209 | N-linked (GlcNAc...) asparagine |
|
||
| 216 |
|
|||
| 230 | N-linked (GlcNAc...) asparagine |
|
||
| 239 |
|
|||
| 240 |
|
|||
|
|
G59626AS
G57321FI
G43417UB
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110048 | Alzheimer's disease 15 | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111095 | Fanconi anemia complementation group A | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:1037 | lymphoid leukemia | |
| DOID:1040 | chronic lymphocytic leukemia | |
| DOID:10534 | stomach cancer | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10844 | Japanese encephalitis |
