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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 2
Summary
- UniProt ID
- P21803
- Gene Symbol
-
- Fgfr2
- Bek
- Ect1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003479
- GlyGen
- P21803
- PubChem
- P21803
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Heparin-binding
- Immunoglobulin domain
- Phosphoprotein
- Proto-oncogene
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| nucleus |
| Golgi apparatus |
| plasma membrane |
| cytoplasmic vesicle |
| receptor complex |
| excitatory synapse |
| cell surface |
| GO Term |
|---|
| heparin binding |
| fibroblast growth factor receptor activity |
| fibroblast growth factor binding |
| ATP binding |
Sequence
MVSWGRFICLVLVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEAYVVAPGESLELQCMLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTAARTVDSETWIFMVNVTDAISSGDDEDDTDSSEDVVSENRSNQRAPYWTNTEKMEKRLHACPAANTVKFRCPAGGNPTSTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKNGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVIFCRMKTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLTQPLEQYSPSYPDTSSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 83 | N-linked (GlcNAc...) asparagine | |||
| 123 | N-linked (GlcNAc...) asparagine |
|
||
| 147 | N-linked (GlcNAc...) asparagine |
|
||
| 228 | N-linked (GlcNAc...) asparagine |
|
||
| 241 | N-linked (GlcNAc...) asparagine |
|
||
| 265 | N-linked (GlcNAc...) asparagine | |||
| 297 | N-linked (GlcNAc...) asparagine |
|
||
| 318 | N-linked (GlcNAc...) asparagine | |||
| 331 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G07755XJ
G80920RR
G60834IK
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR2b ligand binding and activation | Mus musculus |
| FGFR2c ligand binding and activation | Mus musculus |
| FRS-mediated FGFR2 signaling | Mus musculus |
| Negative regulation of FGFR2 signaling | Mus musculus |
| PI-3K cascade:FGFR2 | Mus musculus |
| PI3K Cascade | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| Phospholipase C-mediated cascade; FGFR2 | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
