GlyCosmos Portal

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Biglycan

Summary

UniProt ID

P21810

Gene Symbol

BGN
SLRR1A

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0015601

GlyConnect

1042

GlyGen

P21810

PubChem

P21810

RaftProt

P21810

Annotation

Keyword

Aortic aneurysm
Direct protein sequencing
Disease variant
Disulfide bond
Dwarfism
Extracellular matrix
Leucine-rich repeat
Proteoglycan
Reference proteome
Repeat
Signal

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
bone development
articular cartilage development

Displaying **all 10** entries
GO Term
extracellular region
extracellular space
extracellular matrix
collagen-containing extracellular matrix
transport vesicle
extracellular exosome
sarcolemma
Golgi lumen
cell surface
lysosomal lumen

Displaying **all 5** entries
GO Term
cytokine binding
extracellular matrix binding
extracellular matrix structural constituent conferring compression resistance
extracellular matrix structural constituent
glycosaminoglycan binding

Annotation information from UniProt.

Sequence

MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
42	O-linked (Xyl...) (glycosaminoglycan) serine	2590169 32337544		UniProt GlyGen
47	O-linked (Xyl...) (glycosaminoglycan) serine	2590169 32337544		UniProt GlyGen
56			G43417UB	GlyGen
58			G43417UB	GlyGen
180	O-linked (Xyl...) (glycosaminoglycan) serine			UniProt GlyGen
198	O-linked (Xyl...) (glycosaminoglycan) serine			UniProt GlyGen
270	N-linked (GlcNAc...) asparagine	19159218	G53075ES G81637OR G71463BG G05962QB G64394MX G70232NH G55132BD G69521XL G70888PK G92081HT G35541EV G34617SM G93718GY G13131HA G20312EM G80075MS G11629QQ G57776ZS G16125XL G29545VG G30769VJ G41882MT G44753VC G31596VW G68490OW G77669RF G86234IN G60834IK G86795LJ G86880BF G27947YN G90382BL G30970QQ G80479JV G02315DX G85282JO G20528HD G24954UD G63980BQ G83951ZY G26915XM G94470IW G41126SR G87123QX G96577RX G79666IR G81263BG G65019XG G84492TS G92135MA G34989PA G81198YO G40834TG G47012YE G22310AV G45395BF G59324HL G07246CJ G70375MX G02628JF G20706XG G10819WX G66163OV G40926MX G59536GA G14972EH G22625SJ G69107AL G02030ZB G43223CG G49642SA G58954YZ G26330YA G10846ZT G58802FE G60177UT G40574BA G82830MN G78787DI G93683YO G05933EN G83229XP G08918WF G75983OB G00912UN G49906RN G78790NZ G58087IP G27915IV G89098OM G11911BT G87389XI G23505EP G92551JA G08110WX G61256FT G44211QA G70441OD G72797UR G70822IO G87661QW G66760KM G83646BJ G17208MA G63381RX G72667IM G76295SF G62595EF G66621EA G16175ZV G46691LC G80223IX G25418HZ G27126ED G04657PL G25451PN G87051GH G27058EU G84452RH G40664HB G46524LG G51653BI G85582CB G83460ZZ G37509XX G70223PD G10488MI G82592ZH G20425TQ G60033FS G41071NU G91636VS G07755XJ G19379ID G70418MS G86182NS G35253PZ G09197ZW G46902YN G72747WU G44215PV G60923RB G70619PT G06356OH G59626AS G72398FA G73430PD G47448YK G84862VB G08290VR G14994KB G92406TI G46503DX G25079LO G48584BU G70101JE G80920RR G01485JJ G50757KG G73968GN G65184UU G79568CQ G03382KH G42124LM G02886BB G65092SV G23863VK G90659AW G50073PQ G74430RZ G77547TA G64409MC G80333GO G29299MO G83633GK G62765YT G64527OM G47950XN G47644PP G88891KO G10256JP G95177YH G10486CT G50045TK G05049YU G46687AB G28541PG G72735IY G82119TF G90575OW G23719VF G49874UX G11314AS G29880MM G36379GD G02815KT G92275SC G58001LT G37995HC G84225JN G89045VA G98129XB	UniProt GlyGen GlyConnect
311	N-linked (GlcNAc...) asparagine	19159218	G75006KF G13910DJ G13191RB G53075ES G94665LC G11115RO G15127JD G67164EE G39595FH G81637OR G07810QS G71463BG G82443XX G32788FZ G39471UU G05962QB G30740WO G78649WQ G12341GU G15169WU G70232NH G55132BD G37818NZ G69521XL G92081HT G06247RL G93718GY G85677PP G13131HA G77582RK G20312EM G80075MS G11629QQ G57776ZS G16125XL G29545VG G44753VC G68490OW G52358QA G75418YA G99668VU G77669RF G86234IN G60834IK G86795LJ G86880BF G27947YN G28622IK G90382BL G91473PK G30970QQ G80479JV G85282JO G40206WX G20528HD G24954UD G37692EO G78502KD G63980BQ G83951ZY G04854VP G26915XM G94470IW G87123QX G96577RX G79666IR G81263BG G65019XG G92135MA G26403SG G98611JV G43734MM G34989PA G81198YO G40834TG G02528FI G43669FQ G47012YE G22310AV G45395BF G59324HL G07246CJ G70375MX G04672QB G85554PZ G02628JF G20706XG G10819WX G66163OV G40926MX G59536GA G56307ZW G14972EH G22625SJ G02030ZB G43223CG G49642SA G58954YZ G95977AE G37412TK G54612UD G31986NC G10846ZT G58802FE G60177UT G40574BA G82830MN G78787DI G00273SJ G83229XP G08918WF G75983OB G00912UN G48414YA G49906RN G58087IP G27915IV G89098OM G11911BT G87389XI G23505EP G92551JA G08110WX G61256FT G70441OD G72797UR G70822IO G87661QW G83646BJ G96430BV G17208MA G63381RX G72667IM G76295SF G15664MX G62595EF G66621EA G16175ZV G46691LC G80223IX G25418HZ G27126ED G66766XF G04657PL G25451PN G27058EU G84452RH G24528MX G46524LG G51653BI G85582CB G43769HG G83460ZZ G37509XX G51640FO G70223PD G10488MI G82592ZH G60033FS G41071NU G85740DB G91636VS G07755XJ G86182NS G49018RC G35253PZ G46902YN G72747WU G70619PT G06356OH G59626AS G47448YK G08290VR G14994KB G92406TI G46503DX G41840AI G01650EU G25079LO G70101JE G80920RR G47702MW G63041LO G01485JJ G50757KG G73968GN G65184UU G03382KH G42124LM G02886BB G65092SV G23863VK G90659AW G77547TA G31916IQ G45504EY G64409MC G80333GO G12313PD G37399XV G82463GQ G83633GK G62765YT G47950XN G11870QZ G47644PP G88891KO G72790NZ G95177YH G10486CT G05049YU G46687AB G90734RJ G28541PG G18647XP G82119TF G95865ZB G31852PQ G96993FE G90575OW G49955PK G72787SB G23719VF G39446WN G11314AS G57776ZU G36379GD G02815KT G92050GC G92275SC G28681TP G58001LT G54010QB G72197KC G84225JN G89045VA G98129XB	GlycoProtDB UniProt GlyGen GlyConnect
				GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 11 in total

1

2

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Last »
Pathway Name	Organism
A tetrasaccharide linker sequence is required for GAG synthesis	Homo sapiens
CS/DS degradation	Homo sapiens
Chondroitin sulfate biosynthesis	Homo sapiens
Defective B3GALT6 causes EDSP2 and SEMDJL1	Homo sapiens
Defective B3GAT3 causes JDSSDHD	Homo sapiens
Defective B4GALT7 causes EDS, progeroid type	Homo sapiens
Defective CHST14 causes EDS, musculocontractural type	Homo sapiens
Defective CHST3 causes SEDCJD	Homo sapiens
Defective CHSY1 causes TPBS	Homo sapiens
Dermatan sulfate biosynthesis	Homo sapiens

Human Protein Atlas

ENSG00000182492

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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International Collaboration

Acknowledgements