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D(4) dopamine receptor

Summary

UniProt ID

P21917

Gene Symbol

DRD4

Organism

Homo sapiens (human)

External Links

GlyGen: P21917
PubChem: P21917
The Human Metabolome Database: HMDBP02531
The O-GlcNAc Database: P21917
O-GlcNAcAtlas: P21917

Annotation

Keyword

3D-structure
Biological rhythms
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Metal-binding
Palmitate
Reference proteome
Repeat
Sodium
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **21 - 30** of 33 in total

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GO Term
negative regulation of cytosolic calcium ion concentration
positive regulation of dopamine uptake involved in synaptic transmission
inhibitory postsynaptic potential
phospholipase C-activating dopamine receptor signaling pathway
regulation of potassium ion transport
positive regulation of MAP kinase activity
behavioral response to cocaine
behavioral response to ethanol
social behavior
regulation of circadian rhythm

Displaying **all 6** entries
GO Term
dendrite
postsynapse
glutamatergic synapse
centrosome
plasma membrane
membrane

Displaying entries **1 - 10** of 12 in total

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GO Term
metal ion binding
serotonin binding
neurotransmitter receptor activity
dopamine binding
epinephrine binding
norepinephrine binding
potassium channel regulator activity
SH3 domain binding
identical protein binding
dopamine neurotransmitter receptor activity, coupled via Gi/Go

Annotation information from UniProt.

Sequence

MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites