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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Summary
- UniProt ID
- P22413
- Gene Symbol
-
- ENPP1
- M6S1
- NPPS
- PC1
- PDNP1
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P22413
- PubChem
- P22413
- The Human Metabolome Database
- HMDBP00119
- The O-GlcNAc Database
- P22413
Annotation
- Keyword
-
- 3D-structure
- Biomineralization
- Calcium
- Cell membrane
- Diabetes mellitus
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydrolase
- Metal-binding
- Obesity
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal-anchor
- Transmembrane helix
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| cell surface |
| extracellular space |
| lysosomal membrane |
| plasma membrane |
| membrane |
| basolateral plasma membrane |
Sequence
MERDGCAGGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAPMDVGEEPLEKAARARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFGNCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTFSQED
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 179 | N-linked (GlcNAc...) asparagine | |||
| 285 | N-linked (GlcNAc...) asparagine | |||
| 341 | N-linked (GlcNAc...) asparagine | |||
| 477 | N-linked (GlcNAc...) asparagine | |||
| 578 |
|
|||
| 585 | N-linked (GlcNAc...) asparagine | |||
| 643 | N-linked (GlcNAc...) asparagine | |||
| 700 | N-linked (GlcNAc...) asparagine | |||
| 731 | N-linked (GlcNAc...) asparagine | |||
| 748 | N-linked (GlcNAc...) asparagine |
|
G80920RR
G92081HT
G47518TP
G77582RK
G20312EM
G11629QQ
G68490OW
G95133RI
G86795LJ
G92135MA
G45395BF
G43223CG
G60177UT
G83229XP
G87661QW
G25418HZ
G25451PN
G27058EU
G84452RH
G83460ZZ
G41071NU
G07246CJ
G83646BJ
G10773YW
G96091TT
G51640FO
G49018RC
G72747WU
G70619PT
G20210JR
G92062TF
G63041LO
G02886BB
G90659AW
G59924QI
G84820NF
G47644PP
G28541PG
G05724UK
G46503DX
G70232NH
G85282JO
G27915IV
G84225JN
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Vitamin B2 (riboflavin) metabolism | Homo sapiens |
| Vitamin B5 (pantothenate) metabolism | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11476 | osteoporosis | |
| DOID:11502 | mitral valve insufficiency | |
| DOID:1156 | chondrocalcinosis | |
| DOID:11612 | polycystic ovary syndrome | |
| DOID:11634 | myxedema | |
| DOID:11714 | gestational diabetes | |
| DOID:11716 | prediabetes syndrome | |
| DOID:11830 | myopia | |
| DOID:11847 | coronary thrombosis | |
| DOID:11981 | morbid obesity |
